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General Information
Symbol
Dmel\heph03429
Species
D. melanogaster
Name
FlyBase ID
FBal0009467
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{PZ} insertion in a large intron of heph.

Insertion components
P{PZ}heph03429
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

57.4% of embryos derived from homozygous female germline clones stop developing before cuticle formation, and 27.7% show severe morphological defects that prevents analysis of the head. 12% of the analysable embryos lack head structures.

Homozygous clones result in autonomous loss of wing vein differentiation. Wing veins are only completely missing when dorsal and ventral clones coincide. Homozygous clones induce ectopic wing margin. Dorsal or ventral clones that apparently intersect the normal margin result in nicks in the wing margin. Occasionally, clones that induce ectopic wing margin also induce small outgrowths and overgrowth of adjacent wing tissue.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhancer of
Statement
Reference

heph03429 is a non-enhancer of visible | somatic clone phenotype of DlRevF10

Suppressor of
Statement
Reference

heph[+]/heph03429 is a suppressor | partially of visible | dominant phenotype of fngD4

NOT Suppressor of
Statement
Reference

heph03429 is a non-suppressor of visible | somatic clone phenotype of DlRevF10

Phenotype Manifest In
NOT Enhancer of
Statement
Reference

heph03429 is a non-enhancer of wing vein | somatic clone phenotype of DlRevF10

Suppressor of
Statement
Reference

heph[+]/heph03429 is a suppressor | partially of wing margin phenotype of fngD4

heph[+]/heph03429 is a suppressor | partially of wing phenotype of fngD4

NOT Suppressor of
Statement
Reference

heph03429 is a non-suppressor of wing vein | somatic clone phenotype of DlRevF10

Additional Comments
Genetic Interactions
Statement
Reference

The loss of wing margin seen in fngD4/+ flies is partially rescued by heph03429. Clones mutant for both heph03429 and DlRevF10 have an autonomous thick veins phenotype and are associated with non-autonomous vein differentiation in neighbouring tissue, as occurs in DlRevF10 single mutant clones.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Complementation statment based on male sterile phenotype.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

A. Spradling.

Comments
Comments

Complements: l(3)0384703847. Complements: l(3)0649706497. Complements: l(3)0688606886. Complements: l(3)L1022L1022. Complements: l(3)L7321L7321. Complements: l(3)rH304rH304.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (9)