FB2025_01 , released February 20, 2025
Allele: Dmel\loj04026
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General Information
Symbol
Dmel\loj04026
Species
D. melanogaster
Name
FlyBase ID
FBal0009499
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description

P{PZ} insertion within the open reading frame of the loj classes I-III transcripts.

Allele components
Component
Use(s)
Inserted element
Encoded product / tool
Mutations Mapped to the Genome
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The oviposition defects seen in loj00898/loj04026 mutant females cannot be rescued through feeding the flies either octopamine or glutamate.

loj00898/loj04026 mutants show oviposition defects rendering them sterile.

Homozygous and loj04026/Df(3L)ZN47 females mate with latency and frequency similar to that of control females when mated to wild-type males.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments

Expression of lojScer\UAS.N9d in octopaminergic neurons under the control of either Scer\GAL4ptc-559.1 or Scer\GAL4C164 rescues the egg deposition defects seen in loj00898/loj04026 mutant females. Expression of lojScer\UAS.N9d under the control of the neuropeptidergic driver Scer\GAL4dimm-929 also rescues the phenotype.

Expression of lojScer\UAS.N9d using Scer\GAL4SG18.1 rescues oviposition behaviour and sterility of loj00898/loj04026 mutants.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

A. Spradling.

The reduced viability of homozygotes of the "l(3)04026" line may to be due to a second site mutation; loj04026/loj00898 and loj04026/Df(3L)ZN47 animals eclose in the expected Mendelian ratio.

Comments
Comments

Complements: l(3)0209402094. Complements: l(3)0209403042. Complements: l(3)neo111. Complements: l(3)rP047rP047.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (12)