Open Close
General Information
Symbol
Dmel\Ten-m05309
Species
D. melanogaster
Name
FlyBase ID
FBal0009535
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
odzl(3)5309, l(3)05309, Penh22
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion at nucleotide 4191, 30bp from the beginning of transcription.

Insertion in 5' non-coding region of the transcript.

Insertion components
P{PZ}Ten-m05309
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous and Ten-mCB04632/Ten-m05309 embryos show defects in the guidance of the intersegmental nerve in the periphery.

Mutant larvae do not have defects in the establishment or maintenance of dendritic tiling in class IV dendrite arborisation (da) neurons.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement
Reference

Ten-m[+]/Ten-m05309 is an enhancer of ommatidium phenotype of hhbar3

Additional Comments
Genetic Interactions
Statement
Reference

Ten-m05309/+ enhances the loss of ommatidia phenotype which is seen in hhbar3 homozygotes.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

A. Spradling.

Separable from: CG1049605309b. Evidence suggests that the "l(3)05309" line contains 2 P{PZ} insertions; one at 57E (P{PZ}CG1049605309b) corresponding to the site of the flanking sequence AQ073328, and one at 79E (P{PZ}Ten-m05309) which causes a mutation in Ten-m.

The segmentation defects previously reported to be due to the Ten-m05309 mutation are not due to the Ten-m05309 mutation, but instead are caused by a mutation in the opa gene (represented in by the oparSS allele) present on the TM3-rSS balancer in the original stock.

Comments
Comments

Complements: l(3)0050600506. Complements: Aats-ile00827. Complements: Hem03335. Complements: Csp03988. Complements: l(3)0405304053. Complements: l(3)0907009070. Complements: l(3)04053j8B2. Complements: TyrRneo30.

FlyBase curator comment: FBrf0214744 characterises new loss of function mutations in Ten-m and finds no evidence of a pair-rule segmentation phenotype, in contrast to previous reports. The authors show that the pair-rule phenotype previously reported for a number of Ten-m mutations (including Ten-m05309) was in fact due to a mutation present on the balancer in the original stock. The segmentation phenotype described in FBrf0075161, FBrf0073721, FBrf0098973 and FBrf0204395 for Ten-m05309 has thus been removed from the allele report in FlyBase, since it is not due to the mutation in Ten-m.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (10)
References (20)