FlyBase Allele Report: Dmel\aos[05845]

General Information

Symbol

Dmel\aos⁰⁵⁸⁴⁵

Species

D. melanogaster

Name

FlyBase ID

FBal0009552

Feature type

allele

Associated gene

Dmel\aos

Associated Insertion(s)

P{PZ}aos⁰⁵⁸⁴⁵

Carried in Construct

Also Known As

l(3)05845, aos-lacZ⁰⁵⁸⁴⁵

Key Links

Genomic Maps

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Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Spradling et al., 1999, Schmucker et al., 1997, FlyBase, 1996-, BDGP Project Members, 1994-1999)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:16,483,567..16,483,567 [+]

(Voas and Rebay, 2003, Spradling et al., 1999, Schmucker et al., 1997, FlyBase, 1996-, BDGP Project Members, 1994-1999)

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Cytology

Nature of the lesion

Statement

Reference

The P{PZ}argos⁰⁵⁸⁴⁵ insertion maps within both argos and CG33158 (nested genes).

(FlyBase, 1996-)

Insertion components

P{PZ}aos⁰⁵⁸⁴⁵

Product class / Tool use(s)

Encoded product / tool

Tagged with

nuclear protein localization tag

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Phenotype Manifest In

Bolwig nerve

(Schmucker et al., 1997)

Bolwig organ

(Schmucker et al., 1997)

eye | posterior (with aos^Δ7)

(Voas and Rebay, 2003)

Detailed Description

Statement

Reference

argos^Δ7/argos⁰⁵⁸⁴⁵ escaper adults have extensive blistering along the posterior edge of the eye.

(Voas and Rebay, 2003)

The cohesion of the Bolwig's organ is disrupted and the Bolwig's nerve shows defasciculation and misprojection.

(Schmucker et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

aos[+]/aos⁰⁵⁸⁴⁵ is an enhancer of visible | dominant phenotype of Snr1^E1

(Curtis et al., 2011)

NOT Enhancer of

Statement

Reference

aos⁰⁵⁸⁴⁵ is a non-enhancer of visible phenotype of CanB^GMR.PS, Pp2B-14D^act.GMR

(Sullivan and Rubin, 2002)

NOT Suppressor of

Statement

Reference

aos⁰⁵⁸⁴⁵ is a non-suppressor of visible phenotype of CanB^GMR.PS, Pp2B-14D^act.GMR

(Sullivan and Rubin, 2002)

Phenotype Manifest In

Enhanced by

Statement

Reference

aos^Δ7/aos⁰⁵⁸⁴⁵ has eye phenotype, enhanceable by rno³/rno[+]

(Voas and Rebay, 2003)

Enhancer of

Statement

Reference

aos[+]/aos⁰⁵⁸⁴⁵ is an enhancer of wing vein | ectopic phenotype of Snr1^E1

(Curtis et al., 2011)

NOT Enhancer of

Statement

Reference

aos⁰⁵⁸⁴⁵ is a non-enhancer of eye phenotype of CanB^GMR.PS, Pp2B-14D^act.GMR

(Sullivan and Rubin, 2002)

NOT Suppressor of

Statement

Reference

aos⁰⁵⁸⁴⁵ is a non-suppressor of eye phenotype of CanB^GMR.PS, Pp2B-14D^act.GMR

(Sullivan and Rubin, 2002)

Additional Comments

Genetic Interactions

Statement

Reference

The eye blistering phenotype seen in argos^Δ7/argos⁰⁵⁸⁴⁵ escaper adults is enhanced by rno³/+, so that it covers much of the eye.

(Voas and Rebay, 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

aos^rJ812

(BDGP Project Members, 1994-1999)

aos^rQ526

(BDGP Project Members, 1994-1999)

Fails to complement

aos^rJ472

(BDGP Project Members, 1994-1999)

aos⁰⁵⁹⁵⁹

(BDGP Project Members, 1994-1999)

aos⁰³⁶³⁹

(BDGP Project Members, 1994-1999)

aos^j5E11

(BDGP Project Members, 1994-1999)

aos^03032a

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

11674

P{PZ}aos⁰⁵⁸⁴⁵ CG33158⁰⁵⁸⁴⁵ ry⁵⁰⁶/TM3, ry^RK Sb¹ Ser¹

Notes on Origin

Discoverer

A. Spradling.

Comments

Complements: Mo25⁰⁰²⁷⁴. Complements: l(3)73Ah⁰²⁵⁴⁰. Complements: Baldspot⁰³²²⁹. Complements: l(3)10532¹⁰⁵³². Complements: l(3)j10E8^j10E8. Complements: l(3)s3123^s3123.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

aos⁰⁵⁸⁴⁵

(Voas and Rebay, 2003)

argos⁰⁵⁸⁴⁵

(Curtis et al., 2011)

gil⁰⁵⁸⁴⁵

l(3)05845

(Spradling et al., 1999, Schmucker et al., 1997)

l(3)05845⁰⁵⁸⁴⁵

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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