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General Information
Symbol
Dmel\Atx206490
Species
D. melanogaster
Name
FlyBase ID
FBal0009566
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(3)06490
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{PZ} insertion in the 5' untranslated region, 235bp upstream of the putative start codon.

Insertion components
P{PZ}Atx206490
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adult Atx2X1/Atx206490 transheterozygotes also bearing either Atx2ΔmIDR or Atx2ΔcIDR, but not Atx2+t10.4, exhibit significantly lower long-term olfactory habituation, as compared to controls.

Homozygous clones in the retina result in a mildly disorganised ommatidial pattern and a slight reduction in eye size. Females carrying homozygous germ line clones are completely sterile and fail to lay eggs. Most egg chambers in these females can proceed normally through the early and middle stages of oogenesis, but arrest at the stage when the nurse cells rapidly transfer their contents to the oocyte. The arrested egg chambers have enlarged nurse cells and a small poorly developed oocyte. The actin filaments that normally tether the nurse cell nuclei mostly fail to form. The nurse cell nuclei are inappropriately positioned close to the ring canals and are sometimes seen to stretch partially through the ring canals.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference
Suppressor of
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The poor rhythmicity of adult circadian locomotor activity under free-running (~constant darkness) conditions observed in flies expressing Not1JF03096 under the control of Scer\GAL4P2.4.Pdf is further worsened by combination with a single copy of Atx206490.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

A. Spradling.

Comments
Comments

Precise excision of the P{PZ} element reverts the mutant phenotype.

Complements: Tm102299. Complements: l(3)j6A6j6A6. Complements: l(3)neo441. Complements: Tm1s2958.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (8)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (11)