FlyBase Allele Report: Dmel\klu[10052]

General Information

Symbol

Dmel\klu¹⁰⁰⁵²

Species

D. melanogaster

Name

FlyBase ID

FBal0009618

Feature type

allele

Associated gene

Dmel\klu

Associated Insertion(s)

P{PZ}klu¹⁰⁰⁵²

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Yang et al., 1997)

Progenitor genotype

Associated Insertion(s)

P{PZ}klu¹⁰⁰⁵²

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:11,008,944..11,009,189 [+]

(Melcher and Pankratz, 2005, Spradling et al., 1999, Braun et al., 1997, Yang et al., 1997, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal feeding behavior | larval stage (with klu^212lR51C)

(Melcher and Pankratz, 2005)

abnormal feeding behavior | larval stage (with klu⁰⁹⁰³⁶)

(Melcher and Pankratz, 2005)

lethal | recessive

(Spradling et al., 1999, Yang et al., 1997)

partially lethal - majority die

partially lethal - majority die | recessive

(Braun et al., 1997, Berkeley Drosophila Genome Project, 1993.6.1)

Phenotype Manifest In

ganglion mother cell GMC4-2b

(Yang et al., 1997)

larval RP2 motor neuron

(Yang et al., 1997)

larval RP2 motor neuron of abdominal 1 neuromere

(Yang et al., 1997)

Detailed Description

Statement

Reference

klu¹⁰⁰⁵²/klu⁰⁹⁰³⁶ and klu^212lR51C/klu¹⁰⁰⁵² larvae show a feeding defect in which food becomes lodged in the pharynx.

(Melcher and Pankratz, 2005)

49% of hemisegments T2-A1 have duplicated RP2 neurons in homozygous embryos, but no duplications are seen in hemisegments A2-A8. The duplication is due to the transformation of ganglion mother cell (GMC) 4-2b to a GMC4-2a fate.

(Yang et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

klu¹⁰⁰⁵² dominantly suppresses the rough eye phenotype seen in In(1)rst³ flies.

(Rusconi et al., 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

klu⁰⁹⁰³⁶

(Melcher and Pankratz, 2005)

klu^rJ903a

(BDGP Project Members, 1994-1999)

klu⁰⁹⁰³⁶

(BDGP Project Members, 1994-1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

A. Spradling.

Comments

Complements: l(3)01239⁰¹²³⁹. Complements: l(3)03691⁰³⁶⁹¹. Complements: l(3)01239^j9B4.

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

P1741

(Yang et al., 1997)

klu¹⁰⁰⁵²

klumpfuss^P10052

(Rusconi et al., 2004)

l(3)10052

(Spradling et al., 1999)

l(3)10052¹⁰⁰⁵²

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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