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General Information
Symbol
Dmel\hyd15
Species
D. melanogaster
Name
FlyBase ID
FBal0010246
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

hyd15/hydC017 mutants exhibit abnormalities in spermatogenesis. One such abnormality is for nuclei scattered through the elongated cysts to exhibit a round shape instead of a 'needle' shape. In rare cases, the group of needle-shaped nuclei can be found in the correct place in the cyst; however, some of the nuclei are evidently incorrectly condensed. Approximately 90% of nuclei and micronuclei do not reach the correct cyst pole.

hyd15/hydC017 mutant spermatocytes exhibit defects in cytokinesis such as the formation of two spindles in one meiotic cell. The meiotic products may have unequal amounts of chromatin or mitochondrial material. Centrosome behavior is also affected. Meiotic chromosomes are not correctly attached to the spindle in 50% of hyd15/hydC017 spermatids.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

hyd15 has abnormal cytokinesis phenotype, enhanceable by pAbp[+]/pAbpk10109

Enhancer of
Statement
Reference

hyd[+]/hyd15 is an enhancer of abnormal cytokinesis phenotype of pAbpk10109

NOT Enhancer of
Statement
Reference

hyd[+]/hyd15 is a non-enhancer of visible phenotype of CycEJP

NOT Suppressor of
Statement
Reference

hyd[+]/hyd15 is a non-suppressor of visible phenotype of CycEJP

Phenotype Manifest In
Enhancer of
Statement
Reference
NOT Enhancer of
Statement
Reference

hyd[+]/hyd15 is a non-enhancer of eye phenotype of CycEJP

Suppressor of
Statement
Reference

hyd15 is a suppressor of eye phenotype of EBV\BZLF1GMR.PA

hyd15 is a suppressor of arista | increased number phenotype of obk1

NOT Suppressor of
Statement
Reference

hyd[+]/hyd15 is a non-suppressor of eye phenotype of CycEJP

Other
Additional Comments
Genetic Interactions
Statement
Reference

pAbpk10109/hyd15 trans-heterozygous double mutants exhibit spermatogenesis defects. The morphology of nuclei in the sperm head bundle are indistinguishable from the control but the nuclei are frequently scattered abnormally. Cytokinetic abnormalities are also increased in these double mutants.

The extent of ectopic wing vein formation found in Scer\GAL4GMR.PF CblDv.Scer\UAS flies is enhanced in a hyd15 mutant background but does not affect the eye roughening phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer

Matthews.

Comments
Comments
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (7)