FB2025_01 , released February 20, 2025
Allele: Dmel\Prim2j10B2
Open Close
General Information
Symbol
Dmel\Prim2j10B2
Species
D. melanogaster
Name
FlyBase ID
FBal0010875
Feature type
allele
Associated gene
Dmel\Prim2
Associated Insertion(s)
P{lacW}Prim2j10B2
Carried in Construct
Also Known As
l(3)j10B2
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{lacW}Prim2j10B2
Cytology
Description

P{lacW} insertion in the 5' untranslated region.

(Chen et al., 2000)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      DNAprim[+]/Prim2j10B2 is a suppressor of visible | recessive phenotype of fafFO8

      (Chen et al., 2000)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      DNAprim[+]/Prim2j10B2 is a suppressor of ommatidium phenotype of fafFO8

      (Chen et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Prim2Sfaf240

      (Chen et al., 2000)
      Partially rescued by

      Prim2Sfaf240/Prim2j10B2 is partially rescued by Scer\GAL4Act5C.PI/Prim2UAS.cCa

      (Chen et al., 2000)

      Prim2j10B2 is partially rescued by Scer\GAL4Act5C.PI/Prim2UAS.cCa

      (Chen et al., 2000)
      Comments

      Expression of DNAprimScer\UAS.cCa under the control of Scer\GAL4Act5C.PI partially rescues DNAprimj10B2 homozygotes; flies are viable but nearly sterile. Expression of DNAprimScer\UAS.cCa under the control of Scer\GAL4Act5C.PI partially rescues DNAprimj10B2/DNAprimSfaf240 flies; a few adult escapers are seen that die after 1 day.

      (Chen et al., 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      L. and Y. Jan.

      Comments
      Comments

      Reversion analysis proved that the P{lacW} is responsible for the lethal phenotype.

      (Beaton, 2000.1.31)

      Excision of the P{lacW} element can result in reversion of the phenotype.

      (Chen et al., 2000)

      Complements: eRF100103.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      DNApol-α60j10B2
      DNAprimj10B2
      Prim2j10B2
      l(3)j10B2
      (Chen et al., 2000, Spradling et al., 1999)
      l(3)j10B2j10B2
      (Lukinova et al., 1999, Meister and Braun, 1995.10, BDGP Project Members, 1994-1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)