Allele Dmel\neur^j6B12

General Information
Symbol	Dmel\neur^j6B12	Species	D. melanogaster
Name		FlyBase ID	FBal0010980
Feature type	allele	Associated gene	Dmel\neur

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 3R:4,857,407..4,857,407 (BDGP Project Members, 1994-1999, Sonnenfeld et al., 1997, Spradling et al., 1999)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{lacW}neur^j6B12 (BDGP Project Members, 1994-1999, Sonnenfeld et al., 1997, Spradling et al., 1999)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| recessive (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Phenotype Manifest In
	crystal cell (Milchanowski et al., 2004)
Detailed Description
	Statement Reference The average number of crystal cells per embryo is reduced (to 8.8) in homozygous stage 13-14 embryos compared to wild type (36 +/- 2.2 cells on average). (Milchanowski et al., 2004)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference neur[+]/neur^j6B12 is an enhancer of visible phenotype of Ret^MEN2A.GMR (Read et al., 2005) neur[+]/neur^j6B12 is an enhancer of visible phenotype of Ret^MEN2B.GMR (Read et al., 2005)
NOT Enhancer of
Statement Reference neur[+]/neur^j6B12 is a non-enhancer of visible \| dominant phenotype of Egfr^E1 (Read et al., 2005)
NOT Suppressor of
Statement Reference neur[+]/neur^j6B12 is a non-suppressor of visible \| dominant phenotype of Egfr^E1 (Read et al., 2005)
Phenotype Manifest In
Enhancer of
Statement Reference neur[+]/neur^j6B12 is an enhancer of eye phenotype of Ret^MEN2A.GMR (Read et al., 2005) neur[+]/neur^j6B12 is an enhancer of eye phenotype of Ret^MEN2B.GMR (Read et al., 2005)
NOT Enhancer of
Statement Reference neur[+]/neur^j6B12 is a non-enhancer of eye phenotype of Egfr^E1 (Read et al., 2005)
NOT Suppressor of
Statement Reference neur[+]/neur^j6B12 is a non-suppressor of eye phenotype of Egfr^E1 (Read et al., 2005)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	neur^j2E7 (BDGP Project Members, 1994-1999) neur^j9B8 (BDGP Project Members, 1994-1999) neur^j9B9 (BDGP Project Members, 1994-1999) neur^j9C8 (BDGP Project Members, 1994-1999) neur^rI061 (BDGP Project Members, 1994-1999)
Comments
Stocks ( 2 )
Bloomington	12124 y¹ w^*; P{lacW}neur^j6B12/TM3, Sb¹
Kyoto	111407 y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{GMR-lacZ.C(38.1)}TPN1; P{neoFRT}82B P{lacW}neur^j6B12/TM6B, P{Car20y}TPN1, Tb¹
Notes on Origin
Discoverer	L. and Y. Jan.

Comments
	Complements: l(3)05652⁰⁵⁶⁵². Complements: cpo⁰⁵⁶⁶⁴. (BDGP Project Members, 1994-1999)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	l(3)j6B12 (Spradling et al., 1999) l(3)j6B12^j6B12 neur^j6B12 P12124 (Milchanowski et al., 2004) p^j6B12 (Sonnenfeld et al., 1997)
Name Synonym
Secondary FlyBase IDs

References ( 7 )
Research paper	Read et al., 2005, Genetics 171(3): 1057--1081 A Drosophila model of multiple endocrine neoplasia type 2. [FBrf0190765] Milchanowski et al., 2004, Genetics 168(1): 325--339 Identification and characterization of genes involved in embryonic crystal cell formation during Drosophila hematopoiesis. [FBrf0180297] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489] Sonnenfeld et al., 1997, Development 124(22): 4571--4582 The Drosophila tango gene encodes a bHLH-PAS protein that is orthologous to mammalian Arnt and controls CNS midline and tracheal development. [FBrf0099730]
Personal communication to FlyBase	Beaton, 1999.12.12, Alleles of the lines in the P-element paper. Alleles of the lines in the P-element paper. [FBrf0125032] Meister and Braun, 1995.10, lacZ expression patterns for P{} insertions at Bloomington. lacZ expression patterns for P{} insertions at Bloomington. [FBrf0083714] BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338]

Allele Dmel\neurj6B12

Allele Dmel\neur^j6B12