FB2025_01 , released February 20, 2025
Allele: Dmel\raspm47
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General Information
Symbol
Dmel\raspm47
Species
D. melanogaster
Name
FlyBase ID
FBal0011202
Feature type
allele
Associated gene
Dmel\rasp
Associated Insertion(s)
Carried in Construct
Also Known As
l(3)63Bg
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Wohlwill and Bonner, 1991)
Progenitor genotype
Cytology
Description

Single nucleotide deletion in codon 145, resulting in a frameshift and truncation of the presumptive protein.

(Chamoun et al., 2001)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:3,162,631..3,162,633 [+]
Comment:

Mutation is a single nucleotide deletion in codon 145 resulting in a frameshift and a truncated protein. Position of mutation on reference sequence inferred by FlyBase curator based on author statement.

(Chamoun et al., 2001)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  nervous system disease
      modeled by AtpĪ±DTS1
      (Talsma et al., 2014)
      ameliorates  nervous system disease
      modeled by AtpĪ±CJ5
      (Talsma et al., 2014)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Imaginal discs of homozygous larvae are morphologically normal but differentiate abnormally.

      (Gatti and Baker, 1989)

      Lethal phase is during the early pupal stage. The eye-antenna and leg discs differentiate abnormally, wing and haltere discs are normal. Mitosis is normal.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (8)
      References (12)