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General Information
Symbol
Dmel\did1
Species
D. melanogaster
Name
FlyBase ID
FBal0011246
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Imaginal discs of homozygous larvae are small. Defects in the cell cycle: few or no dividing cells and affects chromosome condensation.

More than 50% of homozygous larvae form puparia, although none of them metamorphose. Mutant larvae have smaller imaginal discs than normal (the maximum size is smaller than the size of wild-type late second instar discs) which cannot differentiate into adult structures when injected into metamorphosing normal larvae. The eye-antenna, leg, wing, haltere and genital discs are abnormal. Late second instar mutant wing discs and eye-antenna-brain complexes injected into wild-type adult females decrease in size for the first 3 days, after which they are no longer detectable. Wings discs from early third instar wild-type larvae injected into late second or early third instar mutant larvae show reduced growth compared to control wild-type discs injected into wild-type larvae. These discs can differentiate when injected into metamorphosing larvae.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
did1
Name Synonyms
Secondary FlyBase IDs
    References (2)