Allele Dmel\lab¹⁵

General Information
Symbol	Dmel\lab¹⁵	Species	D. melanogaster
Name		FlyBase ID	FBal0011528
Feature type	allele	Associated gene	Dmel\lab
Also Known As	lab^vd2

Map ( GBrowse )
Allele class	hypomorphic allele - genetic evidence
Mutagen	X ray
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class	hypomorphic allele - genetic evidence (Merrill et al., 1989, Chouinard and Kaufman, 1991, )
Mutagen	X ray (Merrill et al., 1989)
Mutations Mapped to the Genome

Type Location Additional Notes References insertion site 3R:2,503,308..2,503,921 linked_to=PstI-BamHI_rfrag comment=Approximate position of insertion_site inferred by curator from Figure 1 of FBrf0049820. evidence=experimental (Diederich et al., 1989)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Insertion of about 600bp. (Diederich et al., 1989) deletion
Cytology	Polytene chromosomes normal. (Merrill et al., 1989) Polytene chromosomes normal. (Diederich et al., 1989)
Phenotypic Data
Phenotypic Class

Phenotype Manifest In
	embryonic/larval salivary gland \| embryonic stage (Merrill et al., 1989) embryonic head (Merrill et al., 1989)
Detailed Description
	Statement Reference Hemizygous animals die at the embryonic/first larval instar border. A variable cuticle phenotype is seen, with the severity of the defects correlating with the degree of failure of head involution. The frontal sac appears collapsed, and the pharynx occupies a more anterior position than normal. The salivary glands are missing. (Merrill et al., 1989)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer	Diederich. R. Diederich.

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	lab¹⁵ lab^vd2 (Diederich et al., 1989, Merrill et al., 1989, ) VD-2 (Kaufman et al., 1990)
Name Synonym
Secondary FlyBase IDs

References ( 4 )
Research paper	Chouinard and Kaufman, 1991, Development 113(4): 1267--1280 Control of expression of the homeotic labial (lab) locus of Drosophila melanogaster: evidence for both positive and negative autogenous regulation. [FBrf0053767] Diederich et al., 1989, Genes Dev. 3: 399--414 Isolation, structure, and expression of labial, a homeotic gene of the Antennapedia Complex involved in Drosophila head development. [FBrf0049820] Merrill et al., 1989, Dev. Biol. 135: 376--391 A genetic and developmental analysis of mutations in labial, a gene necessary for proper head formation in Drosophila melanogaster. [FBrf0049494]
Review	Kaufman et al., 1990, Adv. Genet. 27: 309--362 Molecular and genetic organization of the Antennapedia gene complex of Drosophila melanogaster. [FBrf0051115]

Allele Dmel\lab15

Allele Dmel\lab¹⁵