FB2025_01 , released February 20, 2025
Allele: Dmel\mal1
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General Information
Symbol
Dmel\mal1
Species
D. melanogaster
Name
FlyBase ID
FBal0011979
Feature type
allele
Associated gene
Dmel\mal
Associated Insertion(s)
Carried in Construct
Also Known As
ma-l1
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Chovnick et al., 1969)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous viable. Homozygous germline clones display maternal effect phenotype. Embryos derived from heterozygous mothers exhibit a brownish eye colour and the larval Malpighian tubules can be short, bloated and irregularly formed.

      (Perrimon et al., 1989)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Eye color complementation group: IV

      Images (2)
      Stocks (21)
      Notes on Origin
      Discoverer

      Oliver, 1st Dec. 1930.

      Comments
      Comments

      Xanthine dehydrogenase (XDH) and aldehyde oxidase activity are undetectable in extracts of flies. Dithionite/sulfide treatment activates XDH levels to 95% of treated wild-type extracts.

      (Wahl et al., 1982)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      References (12)