Allele Dmel\Abd-B^Mc

General Information
Symbol	Dmel\Abd-B^Mc	Species	D. melanogaster
Name	Microcephalus	FlyBase ID	FBal0012109
Feature type	allele	Associated gene	Dmel\Abd-B

Allele class
Mutagen	spontaneous
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	spontaneous
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference A 9kb EcoRI fragment that covers the iab-7 region is unique to Abd-B^Mc. Associated with a partial duplication of the Abd-B domain. (Hopmann et al., 1995)
Caused by aberration	Dp(3;3)Mc (Duncan and Montgomery, 2002, Hopmann et al., 1995)
Cytology
Phenotypic Data
Phenotypic Class
	fertile \| good viable \| good visible \| dominant
Phenotype Manifest In
	eye scutellar bristle
Detailed Description
	Statement Reference Displays locomotor activity rhythm with an approximately 24h period. (Vosshall and Young, 1995) Eyes of heterozygote small or absent. Scutellar bristles curve upward. Homozygote usually more extreme than heterozygote but not reliably distinguishable. Viability of homozygote varies from 100% down to 40%. ale¹ Abd-B^Mc homozygotes completely eyeless; fertile except when crossed to each other (FBrf0023540). RK1A
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference Ubx^bx-34e Abd-B^Mc double heterozygous females show a significant increase in the level of monoene cuticular hydrocarbons and a significant decrease in the level of 7,11-diene cuticular hydrocarbons compared to wild-type females. (Wicker-Thomas and Jallon, 2001)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 2 )
Bloomington	1729 Pc¹ Abd-B^Mc/TM3, Sb¹
Kyoto	106474 Pc¹ Abd-B^Mc/TM3, Sb¹
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Abd-B^Mc Mc (Vosshall and Young, 1995) Mc¹
Name Synonym	Microcephalus (Duncan and Montgomery, 2002, Hopmann et al., 1995)
Secondary FlyBase IDs

References ( 11 )
Research paper	Wicker-Thomas and Jallon, 2001, Genet. Res. (Camb.) 78(3): 235--242 Control of female pheromones in Drosophila melanogaster by homeotic genes. [FBrf0144886] Hopmann et al., 1995, Genetics 139(2): 815--833 Transvection in the iab-5,6,7 region of the bithorax complex of Drosophila: Homology Independent interactions in trans. [FBrf0080101] Vosshall and Young, 1995, Neuron 15(2): 345--360 Circadian rhythms in Drosophila can be driven by period expression in a restricted group of central brain cells. [FBrf0083505] Kellerman and Miller, 1992, J. Cell Biol. 119: 823--834 An unconventional myosin heavy chain gene from Drosophila melanogaster. [FBrf0056451] Struhl and White, 1985, Cell 43: 507--519 Regulation of the Ultrabithorax gene of Drosophila by other Bithorax complex genes. [FBrf0042035] Lewis, 1978, Nature 276: 565--570 A gene complex controlling segmentation in Drosophila. [FBrf0032262] Golubovsky and Zaharov, 1972, D. I. S. 49: 112 The new autosomal mutation 'almond eye' and its interaction with certain dominant mutants in Drosophila melanogaster. [FBrf0023540] Bateman, 1945, D. I. S. 19: 47 [New mutants report.] [FBrf0065643] Bateman, 1944, D. I. S. 18: 40 [New mutants report.] [FBrf0065642]
Biography	Duncan and Montgomery, 2002, Genetics 161(1): 1--10 E. B. Lewis and the Bithorax complex: part II. From cis-trans test to the genetic control of development. [FBrf0149009]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]

Allele Dmel\Abd-BMc

Allele Dmel\Abd-B^Mc