Reduces meiotic exchange.
Hemizygous male larvae are not sensitive to HN2 and MMS.
Mutants are weakly recombination defective. Mutants do not show sensitivity to UV light, γ rays or X rays. Homozygotes and hemizygotes do not show an increased frequency of spontaneous chromosome aberrations in neuroblast metaphases compared to wild-type larvae.
Females homozygous for mei-2511 exhibit reduced levels of meiotic exchange (to approximately 80% of control levels). The residual exchanges are distributed such that the probability of euchromatic exchange becomes more nearly proportional to polytene-chromosome length (FBrf0023919, Carpenter and Sandler, 1974, FBrf0028329). Both X and fourth chromosomal nondisjunction are slightly elevated, presumably as a consequence of decreased recombination.