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General Information
Symbol
Dmel\mei-2511
Species
D. melanogaster
Name
FlyBase ID
FBal0012146
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
mei-251
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Reduces meiotic exchange.

    Hemizygous male larvae are not sensitive to HN2 and MMS.

    Mutants are weakly recombination defective. Mutants do not show sensitivity to UV light, γ rays or X rays. Homozygotes and hemizygotes do not show an increased frequency of spontaneous chromosome aberrations in neuroblast metaphases compared to wild-type larvae.

    Females homozygous for mei-2511 exhibit reduced levels of meiotic exchange (to approximately 80% of control levels). The residual exchanges are distributed such that the probability of euchromatic exchange becomes more nearly proportional to polytene-chromosome length (FBrf0023919, Carpenter and Sandler, 1974, FBrf0028329). Both X and fourth chromosomal nondisjunction are slightly elevated, presumably as a consequence of decreased recombination.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (3)