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General Information
Symbol
Dmel\mor2
Species
D. melanogaster
Name
FlyBase ID
FBal0012412
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Clones induced early in development (24-48 hours after egg laying) are associated with small or absent halteres and the replacement of proximal haltere structures by proximal wing structures. Clones induced later (48-72 hours after egg laying) often lead to the absence or duplication of halteres, in addition to the appearance of wing structures in the haltere. Homozygous clones also cause transformation of the metanotum to mesonotum. Homozygous clones in the posterior wing cause distortions in wing shape; venation is disrupted and large socketed bristles appear along the posterior wing margin. Homozygous clones in the leg cause the femur and tibia to be short and twisted, and the tarsal segments to be enlarged. Leg clones also contain extra bristles. Clones in the anterior first leg are transformed to anterior second leg or have extra sex comb teeth. Clones in the second leg are twisted, have vesicles of extra tissue, or cause the absence of the entire leg. Tarsal segments are often fused, duplicated or absent. Clones in the third leg often have partial or complete duplications of distal structures, or the entire leg morphology is abnormal. Clones in the first and third legs often cause truncations of the leg. Eggs derived from homozygous germ-line clones fail to hatch and are very abnormal. These abnormalities include collapsed eggs, eggs with partial or no chorions, small or abnormally shaped eggs and fused and thick dorsal appendages.

Mutation changes the level of w expression in ph-plac+3 flies; eye colour is lighter.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

mor2 is an enhancer of visible | dominant phenotype of tna1

Suppressor of
Statement
Reference

mor2/mor[+] is a suppressor of visible | dominant phenotype of Snr1E1

mor2 is a suppressor of visible | dominant | homeotic phenotype of Pcl10

mor2 is a suppressor of visible | dominant | adult stage phenotype of Pcl10

mor2 is a suppressor of visible | dominant phenotype of AntpNs

mor2 is a suppressor of visible | dominant | homeotic phenotype of Pc4

mor2 is a suppressor of visible | dominant | adult stage phenotype of Pc4

mor2/mor[+] is a suppressor of visible | homeotic phenotype of AntpNs, Pc2

NOT Suppressor of
Statement
Reference

mor2 is a non-suppressor of lethal phenotype of Ras85DV12.sev, sevS11.Tag:MYC

Other
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference

mor2 is an enhancer of wing phenotype of tna1

mor2/mor[+] is an enhancer of wing margin phenotype of Scer\GAL4en-e16E, shgUAS.cSa

Suppressor of
Statement
Reference

mor2/mor[+] is a suppressor of wing vein | ectopic phenotype of Snr1E1

mor2/mor[+] is a suppressor | partially of eye phenotype of armS56F.GMR

mor2 is a suppressor of mesothoracic leg phenotype of Pc4

mor2 is a suppressor of metathoracic leg phenotype of Pc4

mor2 is a suppressor of sex comb phenotype of Pc4

mor2 is a suppressor of mesothoracic leg phenotype of Pcl10

mor2 is a suppressor of metathoracic leg phenotype of Pcl10

mor2 is a suppressor of sex comb phenotype of Pcl10

mor2 is a suppressor of antenna phenotype of AntpNs

mor2/mor[+] is a suppressor of antenna phenotype of AntpNs, Pc2

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

γTub23CPl-2 results in a held-out wing phenotype in double heterozygous combination with mor2 (42% penetrance).

brm2 shows some interaction in double heterozygous combination with mor2; slightly more than 20% of flies have held-out wings.

The lethality caused by sevS11.T:Hsap\MYC in combination with Ras85DV12.sev is not suppressed by mor2.

Suppresses the antenna to leg transformation phenotype of Pc2, AntpNs/+. Causes between 50% and 100% suppression of the Pc4/+ extra sex combs phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (21)