Allele Dmel\ninaA⁹

General Information
Symbol	Dmel\ninaA⁹	Species	D. melanogaster
Name		FlyBase ID	FBal0012967
Feature type	allele	Associated gene	Dmel\ninaA
Also Known As	ninaA^G89S

Map ( GBrowse )
Allele class
Mutagen	ethyl methanesulfonate
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	ethyl methanesulfonate (Ondek et al., 1992)
Mutations Mapped to the Genome

Type Location Additional Notes References point mutation 2L:877,626..877,626 comment=Site of nucleic acid substitution inferred by FlyBase based on reported amino acid change evidence=experimental na_change=G877626A pr_change=G89S\|ninaA-PA reported_pr_change=G89S (Ondek et al., 1992)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Amino acid replacement: G89S. (Ondek et al., 1992)
Cytology
Phenotypic Data
Phenotypic Class
	visible \| recessive (Ondek et al., 1992)
Phenotype Manifest In

Detailed Description
	Statement Reference Deep pseudopupil score of 2. (Ondek et al., 1992)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer	Ondek.

Comments
	Strong ninaE allele. Fails to interact with P{Rh1-His}. (Baker et al., 1994) This particular substitution was isolated independently twice. (Ondek et al., 1992)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	ninaA⁹ ninaA^G89S (Baker et al., 1994, Ondek et al., 1992)
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Baker et al., 1994, EMBO J. 13(20): 4886--4895 The cyclophilin homolog ninaA functions as a chaperone, forming a stable complex in vivo with its protein target rhodopsin. [FBrf0076436] Ondek et al., 1992, J. Biol. Chem. 267(23): 16460--16466 Genetic dissection of cyclophilin function. Saturation mutagenesis of the Drosophila cyclophilin homolog ninaA. [FBrf0056405]

Allele Dmel\ninaA9

Allele Dmel\ninaA⁹