Allele Dmel\noc^TE35B

General Information
Symbol	Dmel\noc^TE35B	Species	D. melanogaster
Name		FlyBase ID	FBal0013043
Feature type	allele	Created / Updated	2006-08-22/2006-08-22
Associated gene	Dmel\noc

Allele class	amorph
Mutagen	spontaneous
Nature of the Allele
Allele class	amorph (Gubb et al., 1985, Gubb et al., 1986)
Mutagen	spontaneous
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference -108. From the molecular map of the wild-type noc-Adh region (McGill, Chia, Karp and Ashburner, 1988); coordinate 0 an EcoRI restriction site 1321 bp to the left of the start of transcription of the larval Adh transcript; '+' values to the right, '-' values to the left. Insertion of DNA (approximately 5 bands cytologically). (Ashburner et al., 1981) Insertion of a TE element at coordinate -108.2 to -107.5 of the Adh region chromosome walk (FBrf0043115). (Lovering et al., 1991)
Assay mode
Caused by aberration	Tp(1;2)TE35B (Gubb et al., 1985, Ashburner et al., 1999, Ashburner et al., 1999.10.12, Ashburner et al., 1981, Gubb et al., 1986, Lovering et al., 1991, Davis et al., 1997)
Cytology
Phenotypic Data
Phenotypic Class
	viable (Ashburner et al., 1999) visible \| recessive (Davis et al., 1997)
Phenotype Manifest In
	ocellus (Ashburner et al., 1981, Davis et al., 1997) anterior postalar bristle (Ashburner et al., 1981) microchaeta (Ashburner et al., 1981) ocellar bristle (Ashburner et al., 1981) head bristle (Davis et al., 1997)
Detailed Description
	Statement Reference very strong Very strong allele; homozygotes have no ocelli, few interocular microchaetae and reduced numbers of ocellar and anterior postalar bristles. (Ashburner et al., 1981) Lethal in combination with noc^Sco-rv1. Viable in combination with Df(2L)fn7. (Gubb et al., 1985) Almost lethal in trans with noc^Sco-rv1. Enhances the noc^Sco phenotype; noc^Sco/noc^TE35B flies have only about 16 dorsal head and thoracic bristles, compared to 25-27 bristles in noc^Sco/+ heterozygotes. (Gubb et al., 1986) Homozygous flies have bald heads lacking the ocelli and chaetae. Enhances the noc^Sco bristle phenotype. (Davis et al., 1997)
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	noc^Sco-rv1 (Gubb et al., 1985)
Comments
Stocks ( 4 )
Bloomington	2291 z¹ w¹; b¹ noc^TE35B/CyO 4520 Dp(2;2)Cam10, (al¹) dp^ov1 b¹ noc^TE35B pr¹ cn¹ bw¹/CyO, Df(2L)noc20
Kyoto	106763 z¹ w¹; b¹ noc^TE35B/CyO 107774 Dp(2;2)Cam10, (al¹) dp^ov1 b¹ noc^TE35B pr¹ cn¹ bw¹/CyO, Df(2L)noc20
Notes on Origin
Discoverer	Ising.

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	noc^TE35A (Cheah et al., 1994, ) noc^TE35B noc^TE146 (Ashburner and Harrington, 1984, Ashburner et al., 1983, Ashburner et al., 1982, Ashburner et al., 1981) TE146 unnamed (Lovering et al., 1991, Gubb et al., 1986, Gubb et al., 1985)
Name Synonym
Secondary FlyBase IDs

References ( 13 )
Research paper	Ashburner et al., 1999, Genetics 153(1): 179--219 An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster. The Adh region. [FBrf0111326] Davis et al., 1997, Hereditas 126(1): 67--75 Genetic and phenotypic analysis of the genes of the elbow-no-ocelli region of chromosome 2L of Drosophila melanogaster. [FBrf0093413] Cheah et al., 1994, Molec. Cell. Biol. 14(2): 1487--1499 The Drosophila l(2)35Ba/nocA gene encodes a putative Zn finger protein involved in the development of the embryonic brain and the adult ocellar structures. [FBrf0066938] Lovering et al., 1991, Genetics 128: 357--372 The molecular structure of TE146 and its derivatives in Drosophila melanogaster. [FBrf0054145] McGill et al., 1988, Genetics 119: 647--661 The molecular analysis of an antimorphic mutation of Drosophila melanogaster, Scutoid. [FBrf0048235] Gubb et al., 1986, Genetics 112: 551--575 Interactions between white genes carried by a large transposing element and the zeste<up>1</up> allele in Drosophila melanogaster. [FBrf0044464] Chia et al., 1985, J. molec. Biol. 186(2): 689--706 Molecular analysis of the Adh region of the genome of Drosophila melanogaster. [FBrf0043115] Gubb et al., 1985, Chromosoma 92: 116--123 A preliminary genetic analysis of TE146, a very large transposing element of Drosophila melanogaster. [FBrf0042115] Ashburner and Harrington, 1984, Chromosoma 89: 329--337 A cytological analysis of the Scutoid mutation of Drosophila melanogaster, and its induced revertants. [FBrf0040522] Ashburner et al., 1983, Genetics 104: 405--431 The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. [FBrf0039455] Ashburner et al., 1982, Genetics 102: 401--420 The genetics of a small chromosome region of Drosophila melanogaster containing the structural gene for Alcohol dehydrogenase. [FBrf0038047] Ashburner et al., 1981, D. I. S. 56: 186--191 Report of New Mutants. [FBrf0036112]
Personal communication to FlyBase	Ashburner et al., 1999.10.12, Adh. Adh. [FBrf0112153]

Allele Dmel\nocTE35B

Allele Dmel\noc^TE35B