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General Information
Symbol
Dmel\npr31
Species
D. melanogaster
Name
FlyBase ID
FBal0013163
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(1)npr-3
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Imaginal discs of homozygous larvae are missing or degenerate. Defects in the cell cycle: few or no dividing cells, affects chromosome condensation and cell division failures that result in highly polyploid cells.

Larvae do not pupate, but can survive for weeks after reaching the size of the mature wild-type larva. Imaginal discs are small and unstructured throughout larval development and the long survival period. A wild-type ring gland implanted into mutant larvae induces puparium formation.

continues development through larval stage, but does not pupariate. Imaginal discs are very small and structureless; ring glands are normal in size on eighth to tenth day of larval life. Puparium formation can be induced by implantation of wild-type ring glands. Discs missing or degenerate; mitotic index of larval ganglion cells reduced; chromosomes swollen and unevenly condensed; few metaphases polyploid; no chromosome fragmentation seen (Gatti and Baker, 1989). Homozygous cells in ovary lethal (Perrimon, Engstrom and Mahowald, 1984). late larval lethal mitotic phenotype: irregular condensation of chromosomes, polyploids

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

Maternal germline clonal analysis demonstrates cell lethality in homozygous clones.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
  • FBal0007452
References (4)