A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Allele Dmel\pp

General Information
SymbolDmel\ppSpeciesD. melanogaster
NamepeachFlyBase IDFBal0013456
Feature typealleleCreated / Updated2006-08-22/2006-08-22
Associated geneDmel\p
Allele classloss of function
Mutagenspontaneous
hide Nature of the Allele
Allele class
loss of function
(Falcon-Perez et al., 2007)
Mutagen
spontaneous
 
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      Nucleotides 1946-1948 (ATG), part of codons 649-650 of wild-type p are substituted by TT, resulting in a frameshift. The mutated gene encodes residues 1-648 of p, followed by an unrelated segment of 39 amino acids and an early termination codon.
      (Falcon-Perez et al., 2007)
      Assay mode
      Carried on aberration
      TM3-P{Δ2-3}
      (FlyBase Curators, 2006-)
      TM3
      (FlyBase Curators, 2006-, Lindsley and Zimm, 1992, Bloomington Drosophila Stock Center, 1998.5.16)
      TM3βT8
      (FlyBase Curators, 2006-)
      TM3-HBL1.1
      (FlyBase Curators, 2006-)
      TM3-vKb
      (FlyBase Curators, 2006-)
      TM3-vKc
      (FlyBase Curators, 2006-)
      TM3-vCd
      (FlyBase Curators, 2006-)
      TM3-HShid
      (FlyBase Curators, 2006-)
      TM3-DZ
      (FlyBase Curators, 2006-)
      TM3-lacZ-hg
      (FlyBase Curators, 2006-)
      TM3-vSb
      (FlyBase Curators, 2006-)
      TM3-vCe
      (FlyBase Curators, 2006-)
      TM3-vKd
      (FlyBase Curators, 2006-)
      TM3-Pw+-lacZ
      (FlyBase Curators, 2006-)
      TM3-ftz-lacZ
      (FlyBase Curators, 2006-)
      TM3-vTa
      (FlyBase Curators, 2006-)
      TM3-vMa
      (FlyBase Curators, 2006-)
      TM3-vMb
      (FlyBase Curators, 2006-)
      TM3-vMc
      (FlyBase Curators, 2006-)
      TM3-vMd
      (FlyBase Curators, 2006-)
      TM3-P{ftz/lacZ}
      (FlyBase Curators, 2006-)
      TM3-vGa
      (FlyBase Curators, 2006-)
      TM3-vSa
      (FlyBase Curators, 2006-)
      TM3-SC143
      (FlyBase Curators, 2006-)
      TM3-4
      (FlyBase Curators, 2006-)
      TM3-5
      (FlyBase Curators, 2006-)
      TM3-P{UAS-Dl.DN}
      (FlyBase Curators, 2006-)
      TM3-3-10
      (FlyBase Curators, 2006-)
      TM3-GMRargos
      (FlyBase Curators, 2006-)
      TM3-GTY
      (FlyBase Curators, 2006-)
      TM3-STY
      (FlyBase Curators, 2006-)
      TM3-P{ey-FLP.B}3.1
      (FlyBase Curators, 2006-)
      TM3-TCAG
      (FlyBase Curators, 2006-)
      TM3-TCAGB
      (FlyBase Curators, 2006-)
      TM3-TTG
      (FlyBase Curators, 2006-)
      TM3-vCa
      (FlyBase Curators, 2006-)
      TM3-P{ftz/lacC}SC1
      (FlyBase Curators, 2006-)
      Dp(3;3)Cam31
      (Roote, 2000.3.14, Roote, 2004.6.24)
      TM3-krS
      (FlyBase Curators, 2006-)
      Df(3R)Antp2
      (Johnston et al., 1998)
      Df(3R)MAP2
      (Johnston et al., 1998)
      TM3-T2B
      (FlyBase Curators, 2006-)
      CyO-TM3-GFP
      (FlyBase Curators, 2006-, Rudolph et al., 1999)
      TM2-pp
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      TM3-rSS
      (FlyBase Curators, 2006-)
      TM3-St
      (FlyBase Curators, 2006-)
      TM3-ca
      (FlyBase Curators, 2006-)
      TM3-Sr
      (FlyBase Curators, 2006-)
      TM3-vSd
      (FlyBase Curators, 2006-)
      TM3-AS
      (FlyBase Curators, 2006-)
      TM3-Sb
      (FlyBase Curators, 2006-)
      TM3-ry
      (FlyBase Curators, 2006-)
      TM3-D6
      (FlyBase Curators, 2006-)
      C(3R)RM-SB1
       
      TM3-ISPSAS
      (FlyBase Curators, 2006-)
      TM3-rS
      (FlyBase Curators, 2006-)
      TM3-vCb
      (FlyBase Curators, 2006-)
      TM3-P{sevRas1.V12}FK2
      (FlyBase Curators, 2006-)
      TM3-vMe
      (FlyBase Curators, 2006-)
      TM3-SbSer
      (FlyBase Curators, 2006-)
      TM3-rsuS
      (FlyBase Curators, 2006-)
      In(3L)A54
      (Carpenter, 2002.4.2)
      TM3-vSc
      (FlyBase Curators, 2006-)
      Df(3R)LIN
      (Johnston et al., 1998)
      TM3-pAct-GFP
      (FlyBase Curators, 2006-, Reichhart and Ferrandon, 1998.6.8, Reichhart and Ferrandon, 1998)
      Df(3R)Scr
      (Johnston et al., 1998)
      TM3-GFP
      (FlyBase Curators, 2006-, Rudolph et al., 1999)
      TM3-P{ftz-lacZ.ry+}TM3
      (FlyBase Curators, 2006-)
      TM3-P{GAL4-Hsp70.PB}TR2,P{UAS-GFP.Y}TR2
      (FlyBase Curators, 2006-)
      TM3-HoP3B
      (FlyBase Curators, 2006-)
      C(3R)RM-SK2
       
      TM3-UbxD105.17
      (FlyBase Curators, 2006-)
      TM3-ArSS
      (FlyBase Curators, 2006-)
      TM3-P{UAS-y.C}MC2
      (FlyBase Curators, 2006-)
      TM1-pp
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      TM3-P{UAS-Dl.DN}TJ1
      (FlyBase Curators, 2006-)
      TM3-rrSS
      (FlyBase Curators, 2006-)
      In(3LR)sep
       
      TM3-P{35UZ}2
      (FlyBase Curators, 2006-)
      TM3-Thb8
      (FlyBase Curators, 2006-)
      TM3-vKa
      (FlyBase Curators, 2006-)
      TM3-mwh2-ru1
      (FlyBase Curators, 2006-)
      TM3-Ser
      (FlyBase Curators, 2006-)
      Cytology
      hide Phenotypic Data
      hide Phenotypic Class
      visible
      (Duncan and Kaufman, 1975, Falcon-Perez et al., 2007)
      visible (with Df(3R)p25)
      (Falcon-Perez et al., 2007)
      visible (with p37B)
      (Falcon-Perez et al., 2007)
      visible | recessive
       
      eye color defective
      (Duncan and Kaufman, 1975, Falcon-Perez et al., 2007)
      eye color defective (with Df(3R)p25)
      (Falcon-Perez et al., 2007)
      eye color defective (with p37B)
      (Falcon-Perez et al., 2007)
      hide Phenotype Manifest In
      pigment cell
      (Duncan and Kaufman, 1975, Falcon-Perez et al., 2007)
      pigment cell (with p37B)
      (Falcon-Perez et al., 2007)
      pigment cell (with Df(3R)p25)
      (Falcon-Perez et al., 2007)
      hide Detailed Description
      Statement
      Reference
      Eye colour: abnormal with reduced levels of red and brown pigment (20 and 15% of wild-type levels respectively).
      (Falcon-Perez et al., 2007)
      Eye colour: dull ruby.
      (Duncan and Kaufman, 1975)
      pp males that are also mutant for mle4 show darker eye pigmentation with respect their mle4/+ sibs.
      (Hiebert and Birchler, 1994)
      Eye colour: lighter and more orange than p1.
       
      Color autonomous in pp optic disk allowed to undergo metamorphosis in a wild-type host.
      (Beadle and Ephrussi, 1936)
      9% normal red and 15% normal brown pigment.
      (Beadle, 1937)
      hide Interactions
      hide Phenotypic Class
      hideEnhanced by
      Statement
      Reference
      pp has visible phenotype, enhanceable by g2
      (Falcon-Perez et al., 2007)
      pp has eye color defective phenotype, enhanceable by g2
      (Falcon-Perez et al., 2007)
      pp has visible phenotype, enhanceable by or49h
      (Falcon-Perez et al., 2007)
      pp has eye color defective phenotype, enhanceable by or49h
      (Falcon-Perez et al., 2007)
      pp has visible phenotype, enhanceable by ltd1
      (Falcon-Perez et al., 2007)
      pp has eye color defective phenotype, enhanceable by ltd1
      (Falcon-Perez et al., 2007)
      hide Phenotype Manifest In
      hideEnhanced by
      Statement
      Reference
      pp has pigment cell phenotype, enhanceable by g2
      (Falcon-Perez et al., 2007)
      pp has pigment cell phenotype, enhanceable by or49h
      (Falcon-Perez et al., 2007)
      hideNOT suppressed by
      Statement
      Reference
      pp has phenotype, non-suppressible by su(Hw)2
      (Lindsley and Grell, 1968)
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      Eye colour: brownish, with pp/+, wbf/+. Eye colour: brownish, with pp/+, wh/+.
      (Judd, 1955)
      Eye colour: g[2]; p[p] eyes are lighter and have significantly reduced levels of red pigment compared to either single mutant. The brown pigment levels are comparable to those seen in p[p] single mutants. or[49h]; p[p] double mutants also have reduced levels of red pigment but similar levels of brown pigment to p[p] single mutants. Eye colour: car[1]; p[p] eyes are lighter than either single mutant. The levels of red pigment in the double mutants is comparable to that in car[1] single mutant eyes and the level of brown pigment is comparable to p[p] single mutant eyes. Eye colour: ltd[1]; p[p] eyes are relatively lighter than those of either single mutants.
      (Falcon-Perez et al., 2007)
      hide Xenogenetic Interactions
      Statement
      Reference
      hide Complementation & Rescue Data
      Comments
      hide Stocks ( 495 )
      Bloomington
      553
      pp
      2552
      pp e1
      555
      pp cu1
      1649
      Ki1 pp
      1654
      pp by1
      800
      Dfd1 pp
      4042
      Brd1 pp
      1936
      Dhod2 pp
      572
      rnroe-1 pp
      1664
      kniri-1 pp
      Kyoto
      105977
      pp
      106433
      pp by1
      hide Notes on Origin
      Discoverer
      Bridges, 24th Jan. 1913.
      hide Synonyms & Secondary IDs ( 2 )
      Reported As
      Symbol Synonym
      pp
      (Falcon-Perez et al., 2007, )
      Name Synonym
      peach
      (Falcon-Perez et al., 2007, )
      Secondary FlyBase IDs
        hide References ( 23 )
        Generate a list of
        List References by type
        hide Recent research papers ( 1 )
        Falcon-Perez et al., 2007, Traffic 8(2): 154--168
        The Drosophila Pigmentation Gene pink (p) Encodes a Homologue of Human Hermansky-Pudlak Syndrome 5 (HPS5). [FBrf0192474]
        Show all research papers ...