Heterozygotes show a significant increase in double strand break (DSB) repair via homologous recombination and a corresponding decrease in DSB repair by nonhomologous end-joining compared to controls in a somatic DSB repair assay, when whd-y+
is used as the recipient allele bearing the target break site.
17% of heterozygous males have ectopic sex combs on the second leg.
17-20% of T2 legs and 0% of T3 legs have sex combs in heterozygous males.
Heterozygous males sometimes have ectopic sex combs on the second and third legs.
Mutation does not affect the level of w
expression in ph-plac+3
Mutation has no effect on the hhMrt
Transformation of legs 2 and 3 to leg 1.
Haplo-abnormal phenotype is suppressed by a duplication carrying Pc.