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General Information
Symbol
Dmel\Pka-C101272
Species
D. melanogaster
Name
FlyBase ID
FBal0013846
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{PZ} insertion within the first intron.

Insertion components
P{PZ}Pka-C101272
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Germline clones produce abnormal eggs due to abnormal oogenesis: eggs are collapsed. Lethality occurs during the embryonic and larval stages.

Homozygous mutant clones that cross the dorsal ventral compartment boundary cause bifurcations. Clones present at the anterior posterior wing boundary or on the dorsal or ventral surface of the posterior wing compartment have no phenotype. Clones present in the anterior compartment of the male foreleg cause bifurcation.

Homozygous clones in the imaginal disc are capable of inducing morphogenetic furrows that can progress in any direction. Within the clone randomly oriented ommatidia of both chiral forms are observed. Ommatidia born from ectopic furrows do not always rotate towards the equator but they can organise themselves around the ectopic equator. Clones induced close to the normal equator of the eye disc produce an ectopic equator that can hijack the endogenous equator leading to a single equator positioned away from the dorsoventral midline and not necessarily running precisely along the anteroposterior axis.

Homozygous mutant clones in the compound eye demonstrate non-autonomous eye roughening. Bulging of the eye surface is commonly seen in anterior positioned clones, clones in the posterior region are often smooth.

embryonic/L1 larval lethal. l(2)rM692 partially complements l(2)01272 but fails to complement other alleles; in protein kinase A based on flanking DNA sequence.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

A. Spradling.

Comments
Comments

Complements: numb03235. Complements: l(2)0632006320. Complements: zf30Ck02510. Complements: hoipk04901. Complements: hoipk05712. Complements: hoipk07104. Complements: hoipk07607. Complements: pelo1. Complements: ms(2)30C07822.

Mutant phenotype has been reverted by excision of the P-element.

Reversion of the mutant phenotype by P-element excision.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
Pka-C101272
pka-C1l(2)1272
pkaP01272
Name Synonyms
Secondary FlyBase IDs
    References (12)