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General Information
Symbol
Dmel\qrt1
Species
D. melanogaster
Name
FlyBase ID
FBal0014116
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(3)c21R
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Imaginal discs of homozygous larvae are small.

Larvae have small imaginal discs.

Homozygous larvae never form puparia. Mutant larvae have smaller imaginal discs than normal (the maximum size is similar to the size of wild-type mid-third instar discs) which cannot differentiate into adult structures when injected into metamorphosing normal larvae. The eye-antenna, leg, wing, haltere and genital discs are abnormal. The discs reach their maximum size in 7 day old larvae at 25oC and then degenerate. Late second instar mutant wing discs and eye-antenna-brain complexes injected into wild-type adult females grow substantially in in vivo culture, but are unable to differentiate into adult structures when injected into metamorphosing normal larvae. Wings discs from early third instar wild-type larvae injected into late second or early third instar mutant larvae show reduced growth compared to control wild-type discs injected into wild-type larvae. These discs can differentiate when injected into metamorphosing larvae. Homozygous clones induced early in development (until the middle of the second larval instar stage) are significantly smaller than control clones. The frequency and size of clones induced at later times is indistinguishable from controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
l(3)C21R
l(3)SG561
qrt1
Name Synonyms
Secondary FlyBase IDs
    References (3)