FB2025_01 , released February 20, 2025
Allele: Dmel\ras1
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General Information
Symbol
Dmel\ras1
Species
D. melanogaster
Name
FlyBase ID
FBal0014403
Feature type
allele
Associated gene
Dmel\ras
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
heat
spontaneous
(Slee and Bownes, 1995, Nash et al., 1994)
Progenitor genotype
Cytology
Description

Restriction pattern variant, indicating an insertion, in the 1.1kb XhoI fragment that includes the 5' portion of the ras coding region, exons 1, 2 and part of exon 3.

(Nash et al., 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eye colour: dark ruby.

      (Zhimulev et al., 1987)

      25% normal red pigment and 114% normal brown pigment.

      (Nolte, 1959)

      Malpighian tubule colour: nearly wild-type.

      (Brehme and Demerec, 1942)

      Eye colour autonomous in larval optic disks transplanted into wild type hosts.

      (Beadle and Ephrussi, 1936)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT suppressed by
      Statement
      Reference

      ras1 has phenotype, non-suppressible by su(Hw)2

      (Lindsley and Grell, 1968)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (2)
      Stocks (20)
      Notes on Origin
      Discoverer

      Muller, 17th April 1928.

      Comments
      Comments

      Larval Malpighian tubule colour not useful for classification.

      (Brehme and Demerec, 1942)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ras1
      (Popodi et al., 2010-)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)