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General Information
Symbol
Dmel\rib2
Species
D. melanogaster
Name
FlyBase ID
FBal0014573
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
ribIIB44
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G19278301A

Reported nucleotide change:

G?A

Amino acid change:

R58H | rib-PA; R58H | rib-PB; R58H | rib-PC

Reported amino acid change:

R58H

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: R58H.

Nucleotide substitution: G?A. Amino acid replacement: R58H.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In rib2/rib2 or rib2/rib1 larvae, of those with scorable cuticles, small anterior dorsal holes and puckering of the dorsal epidermis occur in 36% of mutants and large dorsal holes occur in 64% of mutants. Denticle belt phenotypes are also seen. The lateral extent of rib2/rib2 denticle belts is narrowed to 27% that of wild-type, rib2/rib1 belts reduced to 46%. A loss of denticle diversity is also seen in the embryos.

Homozygous and rib2/Df(2R)rib-ex12 embryos show defects in tracheal branch outgrowth. A small number of ribP16/rib2 (2.7% expected) escapers survive to adulthood.

weak allele

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

Allelic series: rib2/rib2 < rib2/rib1 = rib2/Df < rib1/rib1 = rib1/Df.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (7)