FlyBase Allele Report: Dmel\rn[roe-1]

General Information

Symbol

Dmel\rn^roe-1

Species

D. melanogaster

Name

FlyBase ID

FBal0014643

Feature type

allele

Associated gene

Dmel\rn

Associated Insertion(s)

Carried in Construct

Also Known As

roe¹

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

spontaneous

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

Mutagen

spontaneous

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Ma et al., 1996, Cavener et al., 1986)

Phenotype Manifest In

eye

(Ma et al., 1996, Cavener et al., 1986)

ommatidium

(Cavener et al., 1986)

Detailed Description

Statement

Reference

rn^roe-1/rn^roe-3 adult eyes show a mild small and rough eye phenotype.

(Melicharek et al., 2008)

Homozygotes exhibit a small rough eye phenotype.

(Ma et al., 1996)

Rough eye: irregular facets. Acts in dosage sensitive manner.

(Cavener et al., 1986)

RK1. phenotype stronger over a deletion than homozygous. Produces a slight roughening of the eye owing to the irregular disposition of the facets; interommatidial bristles lost from posterior portion of the eye. Extreme expression in mutant/deficiency heterozygotes and more so in deficiency homozygotes; enhanced roughening and posterior loss of ommatidial bristles; in addition the eye is reduced in size and remaining interommatidial bristles are clumped.

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

rn^roe-1 is an enhancer of phenotype of gl³

(Ma et al., 1996)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

rn^13-1

(Shilkova et al., 2000)

Comments

Images (1)

Holtzman, S. and Kaufman, T. (2013)

Mutant

Wild-type

Stocks (77)

Bloomington

572

rn^roe-1 p^p

1666

Ki¹ rn^roe-1 p^p

997

Df(3L)AC1, rn^roe-1 p^p/TM3, Sb¹

1901

Df(3R)MAP11, Ki¹ rn^roe-1 p^p/TM3, Sb¹

2393

Df(3R)WIN11, Ki¹ rn^roe-1 p^p/TM3, Sb¹

1317

Df(3L)st-e4, Ki¹ rn^roe-1 p^p/TM6B, Tb¹

2416

Ki¹ mab¹ rn^roe-1 p^p/TM3, Sb¹

Kyoto

105986

rn^roe-1 p^p

106699

Df(3L)AC1, rn^roe-1 p^p/TM3, Sb¹

101654

In(1)w^m4h ; Ki¹ rn^roe-1 p^p

106566

Df(3R)MAP11, Ki¹ rn^roe-1 p^p/TM3, Sb¹

107306

Df(3R)WIN11, Ki¹ rn^roe-1 p^p/TM3, Sb¹

More stocks available...

Notes on Origin

Discoverer

Markowitz, July 1961.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

rn^roe-1

roe¹

(Melicharek et al., 2008, Shilkova et al., 2000, Phippen and Parkhurst, 1999, Ma et al., 1996, Cavener et al., 1986, Lewis et al., 1980, Markowitz, 1963)

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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