FB2025_01 , released February 20, 2025
Allele: Dmel\Polr2A7
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General Information
Symbol
Dmel\Polr2A7
Species
D. melanogaster
Name
FlyBase ID
FBal0014664
Feature type
allele
Associated gene
Dmel\Polr2A
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Voelker et al., 1985)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethal in combination with RpII215Ubl. Ubx effect inhibited in transheterozygotes with other interacting alleles.

      (Lindsley and Zimm, 1992)

      The capitellum of the haltere shows a partial transformation to wing blade in heterozygotes. Enhances the bristle duplication phenotype of Dl7 heterozygotes. 65% of males have one to six sex comb teeth on the second tarsal segment of their first legs.

      (Mortin et al., 1988)

      Survives at 28oC with nearly wild-type viability, but is lethal at lower temperatures.

      (Voelker et al., 1985)

      Cold-sensitive mutation.

      (Mortin and Kaufman, 1982)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Baker.

      (Voelker et al., 1985)
      Comments
      Comments

      Degree of transformation of the haltere when heterozygous: RpII215H1 < RpII2157 < RpII215K2 < RpII2154 < RpII215Ubl.

      (Mortin et al., 1988)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (7)
      Reported As
      Symbol Synonym
      C11
      (Mortin et al., 1988)
      C11-138
      (Voelker et al., 1985)
      Polr2A7
      RpII2157
      RpII215C11-138
      (Lindsley and Zimm, 1992)
      RpIIC11
      (Mortin and Kaufman, 1982)
      UblC11
      Name Synonyms
      Secondary FlyBase IDs
        References (5)