Allele Dmel\RpII215¹⁰⁸

General Information
Symbol	Dmel\RpII215¹⁰⁸	Species	D. melanogaster
Name		FlyBase ID	FBal0014765
Feature type	allele	Associated gene	Dmel\RpII215

Allele class	amorphic allele - genetic evidence
Mutagen	ethyl methanesulfonate
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class	amorphic allele - genetic evidence (Mortin and Kaufman, 1982)
Mutagen	ethyl methanesulfonate (Perrimon et al., 1984)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	cell lethal \| germline clone (Perrimon et al., 1984) lethal \| embryonic stage (Perrimon et al., 1984) lethal \| embryonic stage \| recessive (Perrimon et al., 1989) lethal \| recessive (Krasnoselskaya et al., 1998, Kim et al., 1994)
Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
NOT suppressed by
Statement Reference RpII215¹⁰⁸ has lethal phenotype, non-suppressible by RpII140^S1 (Kim et al., 1994) RpII215¹⁰⁸ has lethal phenotype, non-suppressible by RpII140^S2 (Kim et al., 1994) RpII215¹⁰⁸ has lethal phenotype, non-suppressible by RpII140^S5 (Kim et al., 1994) RpII215¹⁰⁸ has lethal phenotype, non-suppressible by RpII140^S6 (Kim et al., 1994) RpII215¹⁰⁸ has lethal phenotype, non-suppressible by RpII140^S7 (Kim et al., 1994) RpII215¹⁰⁸ has lethal phenotype, non-suppressible by RpII140^S8 (Kim et al., 1994) RpII215¹⁰⁸ has lethal phenotype, non-suppressible by RpII140^S11 (Kim et al., 1994) RpII215¹⁰⁸ has lethal phenotype, non-suppressible by RpII140^S12 (Kim et al., 1994)
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference The recessive lethality of RpII215¹⁰⁸ is not rescued by one copy of RpII140^S1, RpII140^S2, RpII140^S5, RpII140^S6, RpII140^S8, RpII140^S7, RpII140^S11 or RpII140^S12. (Kim et al., 1994)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer	Lefevre.

Comments
	Maternal germline clonal analysis demonstrates cell lethality in homozygous clones. (Perrimon et al., 1989)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	DF912 (Perrimon et al., 1989) l(1)DF912 (Perrimon et al., 1984, ) RpII215¹⁰⁸ RpIIⁿ² (Mortin and Kaufman, 1982) Ublⁿ²
Name Synonym
Secondary FlyBase IDs

References ( 6 )
Research paper	Krasnoselskaya et al., 1998, Mol. Gen. Genet. 258(5): 457--465 Selection and analysis of rare second-site suppressors of Drosophila RNA polymerase II mutations. [FBrf0103303] Kim et al., 1994, J. Mol. Biol. 244(7): 13--22 Molecular modeling of RNA polymerase II mutations onto DNA polymerase I. [FBrf0103162] Perrimon et al., 1989, Genetics 121: 333--352 Zygotic lethals with specific maternal effect phenotypes in Drosophila melanogaster. [FBrf0049894] Perrimon et al., 1984, Dev. Biol. 105: 404--414 The effects of zygotic lethal mutations on female germ-line functions in Drosophila. [FBrf0040730] Mortin and Kaufman, 1982, Mol. Gen. Genet. 187(1): 120--125 Developmental genetics of a temperature-sensitive RNA polymerase II mutation in Drosophila melanogaster. [FBrf0038443] Mortin and Lefevre, 1981, Chromosoma 82(2): 237--247 An RNA polymerase II-mutation in Drosophila melanogaster that mimics ultrabithorax. [FBrf0035975]

Allele Dmel\RpII215108

Allele Dmel\RpII215¹⁰⁸