A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Allele Dmel\run25

General Information
SymbolDmel\run25SpeciesD. melanogaster
NameFlyBase IDFBal0014870
Feature typealleleAssociated geneDmel\run
Also Known AsrunYC
Allele classhypomorphic allele - genetic evidence
Mutagenethyl methanesulfonate
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Description
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hide Nature of the Allele
Allele class
hypomorphic allele - genetic evidence
(Torres and Sanchez, 1992, Lindsley and Zimm, 1992, Bernstein and Cline, 1994)
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987, Lindsley and Zimm, 1992)
Mutations Mapped to the Genome
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Progenitor genotype
Nature of the lesion
Statement
Reference
 
 
Cytology
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Statement
Reference
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Statement
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Statement
Reference
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Comments
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Discoverer
Wieschaus.
hide Comments
Used as assay for early dosage compensation in Sxl hypomorphic mutants. Males do not express Sxl, predicting that run25 should have the same phenotype in males irrespective of which loss of function Sxl allele they carry. However the distribution of run25 mutant phenotypes in males varies indicating it is sensitive to genetic background.
(Bernstein and Cline, 1994)
The expression of l(1)sc is altered during stage 9 in homozygous mutant embryos.
(Martin-Bermudo et al., 1991)
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hide Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym
l(1)YC28
(Lindsley and Zimm, 1992)
run25
 
runYC28
(Torres and Sanchez, 1992)
runYC
(Harbecke and Lengyel, 1995, Martin-Bermudo et al., 1991, Tearle and Nusslein-Volhard, 1987)
runtYC
(Macias et al., 1994)
Name Synonym
Secondary FlyBase IDs
hide References ( 10 )
Research paper
Harbecke and Lengyel, 1995, Rouxs Arch. Dev. Biol. 204(5): 308--329
Genes controlling posterior gut development in the Drosophila embryo. [FBrf0082073]
Bernstein and Cline, 1994, Genetics 136(3): 1051--1061
Differential effects of Sex-lethal mutations on dosage compensation early in Drosophila development. [FBrf0072617]
Macias et al., 1994, Mech. Dev. 46(1): 15--25
Genetic factors controlling the expression of the abdominal-A gene of Drosophila within its domain. [FBrf0073799]
Torres and Sanchez, 1992, Genet. Res. (Camb.) 59(3): 189--198
The segmentation gene runt is needed to activate Sex-lethal, a gene that controls sex determination and dosage compensation in Drosophila. [FBrf0056153]
Martin-Bermudo et al., 1991, Development 113(2): 445--454
Distribution and function of the lethal of scute gene product during early neurogenesis in Drosophila. [FBrf0053796]
Gergen, 1987, Genetics 117: 477--485
Dosage compensation in Drosophila: Evidence that daughterless and Sex-lethal control X chromosome activity at the blastoderm stage of embryogenesis. [FBrf0046379]
Gergen and Wieschaus, 1986, Cell 45: 289--299
Dosage requirements for runt in the segmentation of Drosophila embryos. [FBrf0043901]
Wieschaus et al., 1984, Rouxs Arch. Dev. Biol. 193: 296--307
Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. [FBrf0040178]
Book
Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
The Genome of Drosophila melanogaster. [FBrf0066905]
Stock list
Tearle and Nusslein-Volhard, 1987, D. I. S. 66: 209--269
Tubingen mutants and stock list. [FBrf0045941]