Allele Dmel\ry²⁶

General Information
Symbol	Dmel\ry²⁶	Species	D. melanogaster
Name		FlyBase ID	FBal0014931
Feature type	allele	Associated gene	Dmel\ry

Map ( GBrowse )
Allele class	loss of function allele, amorphic allele - genetic evidence
Mutagen	X ray
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class	amorphic allele - genetic evidence (Gray et al., 1991) loss of function allele
Mutagen	X ray (Covington et al., 1984, Gray et al., 1991)
Mutations Mapped to the Genome

Type Location Additional Notes References complex substitution 3R:8,862,693..8,862,694 comment=Nucleotides 2804-2805 (GG) have been replaced with a T (coordinates as in FBrf0046390), resulting in a frameshift. evidence=experimental (Gray et al., 1991)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Nucleotides 2804-2805 (GG) have been replaced with a T (coordinates as in FBrf0046390). This results in a frameshift. (Gray et al., 1991) GG-->T at +2804-5 generating amber stop codon
Cytology
Phenotypic Data
Phenotypic Class
	short lived \| male \| heat sensitive (Simonsen et al., 2007)
Phenotype Manifest In

Detailed Description
	Statement Reference Mutant males have a shortened adult life span compared to controls at 29^o, with a mean life span of 19.8 days. (Simonsen et al., 2007)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments	non-complementing allele
Stocks ( 0 )

Notes on Origin
Discoverer	Schalet.
	Induced on: cu kar.
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	rosy²⁶ (Simonsen et al., 2007) ry²⁶
Name Synonym
Secondary FlyBase IDs

References ( 13 )
Research paper	Simonsen et al., 2007, Genetics 176(2): 1283--1297 Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles. [FBrf0201586] Hilliker et al., 1994, Genetics 137(4): 1019--1026 Meiotic gene conversion tract length distribution within the rosy locus of Drosophila melanogaster. [FBrf0075014] Gray et al., 1991, Genetics 127: 139--149 Mapping point mutations in the Drosophila rosy locus using denaturing gradient gel blots. [FBrf0054131] Clark et al., 1986, Genet. Res. (Camb.) 47: 109--116 Genetic analysis of the right (3') end of the rosy locus in Drosophila melanogaster. [FBrf0044367] Cote et al., 1986, Genetics 112: 769--783 Molecular mapping of the rosy locus in Drosophila melanogaster. [FBrf0044473] Covington et al., 1984, Nucleic Acids Res. 12: 4559--4573 Analysis of xanthine dehydrogenase mRNA levels in mutants affecting the expression of the rosy locus. [FBrf0041588] Wahl et al., 1982, J. Biol. Chem. 257(7): 3958--3962 Drosophila melanogaster mal mutants are defective in the sulfuration of desulfo Mo hydroxylases. [FBrf0038245] Hilliker and Chovnick, 1981, Genet. Res. (Camb.) 38(3): 281--296 Further observations on intragenic recombination in Drosophila melanogaster. [FBrf0036464] Gelbart et al., 1976, Genetics 84: 211--232 Extension of the limits of the XDH structural element in Drosophila melanogaster. [FBrf0028748] Chovnick et al., 1964, Genetics 50: 1245--1259 The rosy cistron in Drosophila melanogaster genetic fine structure analysis. [FBrf0016186] Schalet, 1964, D. I. S. 39: 62--64 [New mutants report.] [FBrf0063858] Chovnick et al., 1962, Am. Nat. 96: 281--296 The resolving power of genetic fine structure analysis in higher organisms as exemplified by Drosophila. [FBrf0014337]
Book	Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp Genetic variations of Drosophila melanogaster. [FBrf0020044]

Allele Dmel\ry26

Allele Dmel\ry²⁶