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General Information
Symbol
Dmel\Sbsbd-2
Species
D. melanogaster
Name
FlyBase ID
FBal0015152
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
sbd2
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The intron between exons 6 and 7 also contains a 7bp tandem repeat (that is also present in SbSpi).

Carried on aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Sbsbd-201 does not enhance the bristle phenotype of the Sbsbd-2 allele.

1% of Sbsbd-201/Sbsbd-2 animals have a malformed leg phenotype.

Heterozygotes have denticles that are smaller, thinner and more variable in size and shape than those in wild type. Hairs appear normal.

Sbsbd-1, Sbsbd-2 and Sbsbd-207 have much milder phenotypes than other 'sbd' alleles. They are viable and not malformed as homozygotes.

Sb1/Sbsbd-2 are more extreme than Sb1/+. Sbsbd-2, Sb1 behaves as a recessive 'sbd' allele but is homozygous lethal; rare escapers more extreme and easy to recognize.

homozygous viable Most bristles about three-fourths normal length although some (i.e., posterior postalars) are shorter. Less extreme than Sbsbd-1. Sbsbd-2/Sb1 has shorter bristles than homozygous Sbsbd-2 or Sb1/+. Sbsbd-2 Sb1/+ + has wild-type bristles (Lewis, 1951). RK1.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
NOT suppressed by
Statement
Reference

Sbsbd-2 has phenotype, non-suppressible by su(Hw)2

Other
Additional Comments
Genetic Interactions
Statement
Reference

Sbsbd-201/Sbsbd-2 shows a moderate interaction (25-49% of double mutants have at least one malformed leg) with the following mutations: Rho1J3.8/+ and Rho1E3.10/+. Sbsbd-201/Sbsbd-2 shows a weak interaction (5-24% of double mutants have at least one malformed leg) with the following mutations: Df(2R)Jp8/+.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (64)
Notes on Origin
Discoverer

Harnly, Dec. 1927.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (10)