Semilethal: viability 11%.
The testes of hemizygous males are largely filled with cysts at the spermatocyte and early spermatid stages. Many of the cysts containing primary spermatocytes appear to be degenerating. Spermatid maturation is evident in some cysts, although many axonemes are incomplete, lacking the central microtubules or degenerating at an early stage. The axonemal sheath is not completely formed in some cases, and consequently mitochondrial derivatives are associated with cytoplasmic membranes. Induction of paracrystalline material in the mitochondrial derivatives is seen. Spermatid elongation does not proceed very far.
Mutation blocks gene functions that are critical to the development of both reproductive and non-reproductive tissues. Genetic lesions evident prior to meiosis in the male gametes.
11% survival male-sterile