Allele Dmel\sc¹

General Information
Symbol	Dmel\sc¹	Species	D. melanogaster
Name		FlyBase ID	FBal0015189
Feature type	allele	Created / Updated	2006-05-14/2006-05-14
Associated gene	Dmel\sc

Allele class
Mutagen	spontaneous
Nature of the Allele
Allele class
Mutagen	spontaneous (Campuzano et al., 1985)
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference gypsy at 1.9 to 2.4; (Carramolino, Ruiz-Gomez, Guerrero, Campuzano, and Modolell (1982) and Campuzano, Carramolino, Cabrera, Ruiz-Gomez, Villares, Boronat and Modolell (1985). 0 defined as the more distal EcoRI site within the sc^S2 molecular deficiency; positive values extend to the left.) Insertion of gypsy element. (Georgiev and Gerasimova, 1989) Insertion of a gypsy element. (Georgiev et al., 1990)
Assay mode
Caused by insertion	gypsy{}sc¹ (Golovnin et al., 1999, Geyer et al., 1990, Georgiev et al., 1990, Georgiev and Gerasimova, 1989, Campuzano et al., 1985, Nabirochkin et al., 1998, Campuzano et al., 1986)
Carried on aberration	ClB^36d (FlyBase Curators, 2006-) Dp(1;1)Gr Dp(1;1)Th (Patterson, 1932) ClB (FlyBase Curators, 2006-, Lindsley and Zimm, 1992)
Cytology
Phenotypic Data
Phenotypic Class
	visible (Georgiev and Gerasimova, 1989) visible \| recessive (Held, 1990, Fahmy and Fahmy, 1958)
Phenotype Manifest In
	wing (Jack and DeLotto, 1992) mesothoracic tarsal bristle (Held, 1990) mesothoracic tarsal bristle longitudinal row 6.5 (Held, 1990) mesothoracic tarsal bristle longitudinal row 6 (Held, 1990) scutellar bristle (Georgiev and Gerasimova, 1989) anterior dorsocentral bristle (Georgiev and Gerasimova, 1989) ocellar bristle (Georgiev and Gerasimova, 1989, Fahmy and Fahmy, 1958) anterior orbital bristle (Georgiev and Gerasimova, 1989) middle orbital bristle (Georgiev and Gerasimova, 1989) postvertical bristle (Fahmy and Fahmy, 1958)
Detailed Description
	Statement Reference Causes loss or marked reduction in number of scutellar, coxal, ocellar, first and second orbital, anterior notopleural, postvertical, tergital and sternal bristles. Bristle sockets missing; bristle cells absent 19 hr after pupation, when normally present (Lees and Waddington, 1942; Lees and Waddington, 1943). Suppressed by su(Hw) and su(Hw)². RK1. Revertable by X rays (Green, 1961). Flies show a loss or reduction in the number of scutellar, anterior dorsocentral, first and second orbital, ocellar and some other bristles. (Georgiev and Gerasimova, 1989) y²/y^59b flies carrying sc¹ on the y² chromosome have a y² phenotype. (Geyer et al., 1990) The number of bractless bristles on the basitarsi of the second legs is reduced. (Held, 1990) Homozygotes exhibit loss of a third to half of the wing margin chemoreceptors. Double mutants with ct^L32 exhibit an extreme wing phenotype lacking almost all the chemoreceptors and mechanoreceptors. (Jack and DeLotto, 1992) sc^Fah/sc¹ flies show only an occasional absence of postvertical or ocellar bristles. (Fahmy and Fahmy, 1958)
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement Reference ac¹/sc¹ is a suppressor of visible \| conditional - heat sensitive phenotype of H^C2.hs (Johannes and Preiss, 2002)
Phenotype Manifest In
Suppressed by
Statement Reference sc¹ has phenotype, suppressible by su(Hw)² (Georgiev and Gerasimova, 1989, Lindsley and Grell, 1968) sc¹ has phenotype, suppressible by su(Hw)^u1 (Georgiev and Gerasimova, 1989) sc¹ has phenotype, suppressible by su(Hw)^u2 (Georgiev and Gerasimova, 1989) sc¹ has phenotype, suppressible by su(sc)^u1 (Georgiev and Gerasimova, 1992) sc¹ has phenotype, suppressible by su(sc)^u2 (Georgiev and Gerasimova, 1992) sc¹ has phenotype, suppressible by su(sc)^u3 (Georgiev and Gerasimova, 1992)
Suppressor of
Statement Reference ac¹/sc¹ is a suppressor of wing vein \| ectopic \| conditional - heat sensitive phenotype of H^C2.hs (Johannes and Preiss, 2002) ac¹/sc¹ is a suppressor of wing \| conditional - heat sensitive phenotype of H^C2.hs (Johannes and Preiss, 2002) sc[+]/sc¹ is a suppressor of wing margin bristle \| ectopic phenotype of h⁴¹/h[+], ttk^rM730 (Badenhorst et al., 2002)
Additional Comments
Genetic Interactions
Statement Reference The phenotype is affected by mod(mdg4)^ul; the ocellar, first and second orbital, and postvertical bristles are present, while the scutellar bristles are lost completely. (Georgiev and Gerasimova, 1989) The addition of sc¹/Y to h⁴¹/+, ttk^rM730/+ animals leads to an almost complete suppression of the ectopic margin bristle phenotype. (Badenhorst et al., 2002)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 122 )
Bloomington	96 sc¹ 176 y¹ sc¹ 3604 sc¹ z¹ w^DZL
Kyoto	102042 sc¹ ec¹ 101181 sc¹ z¹ w^h 101030 sc¹ z¹ ec¹ 101180 sc¹ z¹ w^ch 101182 sc¹ z¹ w^is 101176 sc¹ w^bl ec¹ 101266 y² sc¹ w^sp1 101025 Dp(1;1)z59d, sc¹ z^59d 101183 sc¹ z¹ w^zmzrb
	More stocks available...
Notes on Origin
Discoverer	Bridges, 22nd Jan. 1916.
	Arose with: dw-sc¹.
Comments
	See Campuzano et al., Cell 40:327--338. (Campuzano et al., 1986) Weak sc allele. (Jack and DeLotto, 1992)
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	sc (Fahmy and Fahmy, 1958) sc¹
Name Synonym
Secondary FlyBase IDs

References ( 28 )

Generate a list of	All references relating to this allele ( 28 )

List References by type	Research paper ( 21 ) Review ( 3 ) FlyBase analysis ( 1 ) Book ( 3 )
Recent research papers (0)
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Allele Dmel\sc1

Allele Dmel\sc¹