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Allele Dmel\sc⁸

General Information
Symbol	Dmel\sc8	Species	D. melanogaster
Name		FlyBase ID	FBal0015197
Feature type	allele	Created / Updated	2006-08-22/2006-08-22
Associated gene	Dmel\sc
Allele class
Mutagen	X ray
Nature of the Allele
Allele class
Mutagen	X ray (Lindsley and Zimm, 1992)
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Progenitor genotype
Nature of the lesion	Statement Reference
Assay mode
Caused by aberration	In(1)sc8 (Campuzano et al., 1985, Golovnin et al., 2003, Dambly-Chaudiere and Ghysen, 1987, Campuzano and Modolell, 1992, Lindsley and Zimm, 1992, Gomez-Skarmeta et al., 1995)
Carried on aberration	FM7c-vHa (FlyBase Curators, 2006-) FM7f-P{ftz-lac} (FlyBase Curators, 2006-) FM7c-FTG (FlyBase Curators, 2006-) FM7c-actLacZ (FlyBase Curators, 2006-) FM7h-NPlacr (FlyBase Curators, 2006-, Heitzler, 1997) FM7c-vKa (FlyBase Curators, 2006-) FM6T8LZ (FlyBase Curators, 2006-) FM7c-10 (FlyBase Curators, 2006-) FM7c-34 (FlyBase Curators, 2006-) FM6-vFa (FlyBase Curators, 2006-) Binsc-3AWS (FlyBase Curators, 2006-) FM6l (FlyBase Curators, 2006-) FM6-l(1)FMa (FlyBase Curators, 2006-) M9 (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 1998.5.16) FM7a (FlyBase Curators, 2006-, Merriam, 1968, Lindsley and Zimm, 1992) M6-ML (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 1998.5.16) FM6-w1 (FlyBase Curators, 2006-) FM6vESB (FlyBase Curators, 2006-) FM6 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) FM7a-m73 (FlyBase Curators, 2006-) FM7g-Nnd-0 (FlyBase Curators, 2006-) FM7a-B+ (FlyBase Curators, 2006-) FM7k (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 1998.5.21) Binsc (FlyBase Curators, 2006-) FM3-vOf (FlyBase Curators, 2006-) FM4 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) Bascy (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 1998.5.16) FM4-vMa   Insc (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) FM6-wc (FlyBase Curators, 2006-) FM4-vAd (FlyBase Curators, 2006-) FM7d (FlyBase Curators, 2006-) Binscy (FlyBase Curators, 2006-) finscy (FlyBase Curators, 2006-) Binsn (FlyBase Curators, 2006-) Binscop (FlyBase Curators, 2006-, Green, 2005.2.15) FM7g-ctns (FlyBase Curators, 2006-) FM6-widm+ (FlyBase Curators, 2006-) FM1-lz+ (FlyBase Curators, 2006-) FM7c-ctS (FlyBase Curators, 2006-) FM3 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) FM4-w1B+ (FlyBase Curators, 2006-) FM7i (FlyBase Curators, 2006-, Heitzler, 1997) FM6-vAb (FlyBase Curators, 2006-) FM4-vAb (FlyBase Curators, 2006-) FM7a-nod4 (FlyBase Curators, 2006-) FM7f (FlyBase Curators, 2006-, Heitzler, 1997) FM7j-B1 (FlyBase Curators, 2006-, Roote, 2001.12.11) FM1 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992, Bloomington Drosophila Stock Center, 1998.5.16) FM7e (FlyBase Curators, 2006-) FM7j (FlyBase Curators, 2006-) FM7i-pAct-GFP (FlyBase Curators, 2006-, Reichhart and Ferrandon, 1998.6.8, Reichhart and Ferrandon, 1998) FM7c (FlyBase Curators, 2006-) Basc (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 1998.5.16) FM4-wfB (FlyBase Curators, 2006-) FM1-B+l (FlyBase Curators, 2006-) Inscy (FlyBase Curators, 2006-) FM4-vAc (FlyBase Curators, 2006-) C(1;YS)5   FM7c-sn+ (FlyBase Curators, 2006-) Bwinscy (FlyBase Curators, 2006-) FM0 (FlyBase Curators, 2006-, Lindsley and Zimm, 1992, Bloomington Drosophila Stock Center, 1998.5.16) FM7w (FlyBase Curators, 2006-) winscy (FlyBase Curators, 2006-) FM6-12 (FlyBase Curators, 2006-) FM7c-B+ (FlyBase Curators, 2006-) FM7h (FlyBase Curators, 2006-) FM4-vAa (FlyBase Curators, 2006-) FM7-l(1)TW241 (FlyBase Curators, 2006-) Binsinscy (FlyBase Curators, 2006-) asc (FlyBase Curators, 2006-, Lindsley and Zimm, 1992) FM6K (FlyBase Curators, 2006-) FM7c-w+ (FlyBase Curators, 2006-) FM7b (FlyBase Curators, 2006-) FM7a-l (FlyBase Curators, 2006-) FM6-vAa (FlyBase Curators, 2006-) FM6-ct83h (FlyBase Curators, 2006-) FM7g (FlyBase Curators, 2006-, Heitzler, 1997) Insc-fu1 (FlyBase Curators, 2006-)
Cytology
Phenotypic Data
Phenotypic Class
	viable (Golovnin et al., 2003) semi-lethal (Hess, 1962, Hess, 1963) visible (Golovnin et al., 2003) visible | recessive (Gomez-Skarmeta et al., 1995)
Phenotype Manifest In
	scutellar bristle (Golovnin et al., 2003) supraalar bristle (Lindsley and Zimm, 1992) sternopleural bristle (Lindsley and Zimm, 1992) macrochaeta (Lindsley and Zimm, 1992) anepisternum (Lindsley and Zimm, 1992) anterior notopleural bristle (Gomez-Skarmeta et al., 1995)
Detailed Description
	Statement Reference The acHw-1 effect interacts strongly with h to produce extremely hairy wings. (Steinberg, 1942) sc8/0 male nearly lethal; survivors show variegation for y and ac; lethality suppressed by a Y chromosome, partially suppressed by parts of the Y. (Hess, 1962) sc8/0 male nearly lethal; survivors show variegation for y and ac; lethality suppressed by a Y chromosome, partially suppressed by parts of the Y. (Hess, 1963) Slight sc; supra-alars, sternopleurals, or other bristles sometimes affected. Extra bristles may be present. Shows acHw-1 effect and may be recognized in heterozygote, homozygote, or male by presence of one or more hairs on anterior mesopleural region. RK2A. (Lindsley and Zimm, 1992) Anterior notopleural macrochaetae are removed. (Gomez-Skarmeta et al., 1995) Mutants show loss of the scutellar bristle. (Golovnin et al., 2003)
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement Reference sc8 has scutellar bristle phenotype, enhanceable by Df(3R)GC14/mod(mdg4)ul (Golovnin et al., 2003) sc8 has scutellar bristle phenotype, enhanceable by mod(mdg4)ul/mod(mdg4)ul (Golovnin et al., 2003) sc8 has scutellar bristle phenotype, enhanceable by su(Hw)7/su(Hw)V (Golovnin et al., 2003)
NOT suppressed by
Statement Reference sc8 has phenotype, non-suppressible by su(Hw)2 (Lindsley and Grell, 1968)
Other
Statement Reference mod(mdg4)ul, sc8 has anterior supraalar bristle phenotype (Golovnin et al., 2003, Golovnin et al., 2003) mod(mdg4)ul, sc8 has humeral bristle phenotype (Golovnin et al., 2003, Golovnin et al., 2003) mod(mdg4)ul, sc8 has presutural bristle phenotype (Golovnin et al., 2003, Golovnin et al., 2003) Df(3R)GC14/mod(mdg4)ul, sc8 has anterior supraalar bristle phenotype (Golovnin et al., 2003, Golovnin et al., 2003) Df(3R)GC14/mod(mdg4)ul, sc8 has humeral bristle phenotype (Golovnin et al., 2003, Golovnin et al., 2003) Df(3R)GC14/mod(mdg4)ul, sc8 has presutural bristle phenotype (Golovnin et al., 2003, Golovnin et al., 2003) sc8, su(Hw)7/su(Hw)V has anterior supraalar bristle phenotype (Golovnin et al., 2003, Golovnin et al., 2003) sc8, su(Hw)7/su(Hw)V has presutural bristle phenotype (Golovnin et al., 2003, Golovnin et al., 2003) sc8, su(Hw)7/su(Hw)V has humeral bristle phenotype (Golovnin et al., 2003, Golovnin et al., 2003)
Additional Comments
Genetic Interactions
Statement Reference In(1)sc8 ; su(Hw)V/su(Hw)7 animals show loss of a number of bristles. Bristle pigmentation is normal in these animals. In(1)sc8 ; mod(mdg4)ul/mod(mdg4)ul and In(1)sc8 ; mod(mdg4)ul/Df(3R)GC14 animals show loss of a number of bristles. Bristle pigmentation is normal in these animals. (Golovnin et al., 2003)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 98 )
Bloomington	796 In(1)sc8, sc8 760 Dp(1;f)101/Df(1)sc8, sc8 wa 762 Dp(1;f)118/Df(1)sc8, sc8 wa 763 Dp(1;f)107/Df(1)sc8, sc8 wa 4444 In(1)sc8, sc8 wa bb* 798 In(1)sc8, sc8 y31d wa 799 In(1)sc8, In(1)dl-49, y31d sc8 764 Dp(1;f)135, y2/Df(1)sc8, sc8 wa
Kyoto	101137 In(1)sc8, sc8 wDZL 103238 Basc, sc8 scS1 wa B1 101072 Df(1)N71 / FM6, y31d sc8 dm1 B1 103090 P{lArB}SW090 / FM6, y31d sc8 dm B ; ry506
	More stocks available...
Notes on Origin
Discoverer	Sidorov, 1929.
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	sc8   scute8 (Greenspan, 2003)
Name Synonym
Secondary FlyBase IDs
References ( 29 )
Generate a list of	All references relating to this allele ( 29 )
List References by type	Research paper  ( 15 ) Review  ( 3 ) Personal communication to FlyBase  ( 5 ) Abstract  ( 2 ) FlyBase analysis  ( 1 ) Book  ( 2 ) Stock list  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2006 Show research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2006 Show reviews ...