A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Allele Dmel\sca2

General Information
SymbolDmel\sca2SpeciesD. melanogaster
NameFlyBase IDFBal0015255
Feature typealleleAssociated geneDmel\sca
Map ( GBrowse ) GBrowse View Helpdetailed view FBal0093789 FBal0015255
Allele class
Mutagenspontaneous
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Description
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FB2013_03
FB2013_02
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hide Nature of the Allele
Allele class
Mutagen
spontaneous
(Ives, 1967)
Mutations Mapped to the Genome
Type
Location
Additional Notes
References
complex substitution
2R:8,687,296..8,687,496
comment=A rearrangement with unknown DNA inserted into intron 3 causing truncation of the protein after K460.
evidence=experimental
(Hu et al., 1995)
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Progenitor genotype
Nature of the lesion
Statement
Reference
Breakpoint in intron III and an insertion of unknown DNA causing truncation of the protein after Lys460 (absence of carboxy terminal sequences).
(Hu et al., 1995)
Cytology
hide Phenotypic Data
hide Phenotypic Class
visible
(Rabinow and Birchler, 1990)
hide Phenotype Manifest In
eye
(Rabinow and Birchler, 1990)
macrochaeta
(Rabinow and Birchler, 1990)
hide Detailed Description
Statement
Reference
Homozygotes exhibit rough eyes and twinned bristles.
(Rabinow and Birchler, 1990)
no reduction in bristle number
 
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Linkouts
hide Interactions
hide Phenotypic Class
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hide Additional Comments
hide Genetic Interactions
Statement
Reference
hide Xenogenetic Interactions
Statement
Reference
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Comments
hide Stocks ( 2 )
Bloomington
4009
sca2
Kyoto
107553
sca2
hide Notes on Origin
Discoverer
Ives, 31st Dec. 1965.
Ives.
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Other Crossreferences
Linkouts
hide Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym
sca2
(Christensen et al., 2008.4.15, Cook and Cook, 2010.5.7)
sca65l31
 
sca65131
(Ives, 1967)
scaG5l31
(Verheyen et al., 1996)
scaG5131
(Verheyen et al., 1996)
Name Synonym
Secondary FlyBase IDs
  • FBal0046406
hide References ( 7 )
Research paper
Verheyen et al., 1996, Genetics 144(3): 1127--1141
Analysis of dominant enhancers and suppressors of activated Notch in Drosophila. [FBrf0090844]
Hu et al., 1995, Genetics 141(2): 607--617
Molecular analysis of scabrous mutant alleles from Drosophila melanogaster indicates a secreted protein with two functional domains. [FBrf0084048]
Rabinow and Birchler, 1990, Genetics 125: 41--50
Interactions of vestigial and scabrous with the Notch locus of Drosophila melanogaster. [FBrf0051947]
Ives, 1972, D. I. S. 48: 16
[New mutants report.] [FBrf0065675]
Ives, 1967, D. I. S. 42: 39
[New mutants report.] [FBrf0063542]
Personal communication to FlyBase
Cook and Cook, 2010.5.7, Isolation and characterization of Df(2R)BSC880.
Isolation and characterization of Df(2R)BSC880. [FBrf0210860]
Christensen et al., 2008.4.15, Isolation and characterization of Df(2R)BSC485.
Isolation and characterization of Df(2R)BSC485. [FBrf0204541]