A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Allele Dmel\Ser1

General Information
SymbolDmel\Ser1SpeciesD. melanogaster
NameFlyBase IDFBal0015427
Feature typealleleCreated / Updated2006-05-15/2006-05-15
Associated geneDmel\Ser
Allele class
Mutagenspontaneous
hide Nature of the Allele
Allele class
Mutagen
spontaneous
(Lindsley and Zimm, 1992)
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      5.5-kb insert at 0 to 3.0 kb.
      (Lindsley and Zimm, 1992)
      Assay mode
      Caused by insertion
      ?{}Ser1
      (Lindsley and Zimm, 1992)
      Carried on aberration
      TM3-vCd
      (FlyBase Curators, 2006-)
      TM3-vCe
      (FlyBase Curators, 2006-)
      TM3-vSa
      (FlyBase Curators, 2006-)
      TM3-P{ey-FLP.B}3.1
      (FlyBase Curators, 2006-)
      TM3-TTG
      (FlyBase Curators, 2006-)
      TM3-vCa
      (FlyBase Curators, 2006-)
      TM3-P{ftz/lacC}SC1
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      CyO-TM3-GFP
      (FlyBase Curators, 2006-, Rudolph et al., 1999)
      TM3-rSS
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      TM3-ca
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 1999.8.10)
      TM3-ry
      (FlyBase Curators, 2006-)
      TM3-D6
      (FlyBase Curators, 2006-, Carpenter, 1998.11.24)
      TM3-ISPSAS
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      TM3-rS
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      TM3-SbSer
      (FlyBase Curators, 2006-, Nicklas and Cline, 1983, Lindsley and Zimm, 1992)
      TM3-vSc
      (FlyBase Curators, 2006-)
      TM3-pAct-GFP
      (FlyBase Curators, 2006-, Reichhart and Ferrandon, 1998.6.8, Reichhart and Ferrandon, 1998)
      TM3-GFP
      (FlyBase Curators, 2006-, Rudolph et al., 1999)
      TM3-P{GAL4-Hsp70.PB}TR2,P{UAS-GFP.Y}TR2
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      TM3-ArSS
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      TM3-P{UAS-y.C}MC2
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      TM3-rrSS
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      TM3-Thb8
      (FlyBase Curators, 2006-)
      TM3-Ser
      (FlyBase Curators, 2006-, Lindsley and Zimm, 1992)
      Cytology
      hide Phenotypic Data
      hide Phenotypic Class
      viable | recessive
      (Lindsley and Zimm, 1992)
      hide Phenotype Manifest In
      wing
      (Lindsley and Zimm, 1992)
      hide Detailed Description
      Statement
      Reference
      Ser1 is homozygous viable; initially thought to be homozygous lethal, but lethality removable by recombination; the closely linked lethal persists in many Ser1-bearing chromosomes. Homozygous Ser1 produces extreme incision of wing margins especially in second posterior cell.
      (Belt, 1971)
      Wings of Ser1/+ and hemizygous Ser1 notched at tip; deepest notch at second posterior cell. In triploids, one dose of Ser1 overlaps wild type. As with other Ser alleles expression suppressed by H and N. Dominant wing phenotype; homozygous viable.
      (Lindsley and Zimm, 1992)
      Wing margin phenotype not affected by Su(dx)sp.
      (Fostier et al., 1998)
      hide Interactions
      hide Phenotypic Class
      hide Phenotype Manifest In
      hideEnhanced by
      Statement
      Reference
      Ser1 has wing phenotype, enhanceable by rnGAL4-13
      (St Pierre et al., 2002)
      Ser1 has wing phenotype, enhanceable by rnGAL4-14
      (St Pierre et al., 2002)
      Ser1 has wing phenotype, enhanceable by rnGAL4-5
      (St Pierre et al., 2002)
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      hide Xenogenetic Interactions
      Statement
      Reference
      hide Complementation & Rescue Data
      Comments
      hide Stocks ( 2676 )
      Bloomington
      3354
      Df(3R)roe/TM3, Ser1
      5915
      Df(3L)E44/TM3, Ser1
      6411
      Df(3L)BSC8/TM3, Ser1
      5744
      Dp(3;3)Cam32/TM3, Ser1
      2371
      flr3/TM3, Ser1
      3355
      Df(3R)kar-Sz8/TM3, Ser1
      Kyoto
      106998
      Df(3R)roe/TM3, Ser1
      108484
      Df(3L)E44/TM3, Ser1
      108775
      Df(3L)BSC8/TM3, Ser1
      108400
      Dp(3;3)Cam32/TM3, Ser1
      106999
      Df(3R)kar-Sz8/TM3, Ser1
      107290
      flr3/TM3, Ser1
      hide Notes on Origin
      Discoverer
      Spencer, 7th Dec. 1935.
      hide Synonyms & Secondary IDs ( 3 )
      Reported As
      Symbol Synonym
      BdS
      (Coyle-Thompson and Banerjee, 1993, Lindsley and Zimm, 1992)
      Ser1
       
      SerBd
      (Speicher et al., 1994)
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 17 )
        Research paper
        St Pierre et al., 2002, Development 129(5): 1273--1281
        Control of Drosophila imaginal disc development by rotund and roughened eye: differentially expressed transcripts of the same gene encoding functionally distinct zinc finger proteins. [FBrf0144823]
        Rudolph et al., 1999, D. I. S. 82: 99--100
        New type of CyO and TM3 green balancers. [FBrf0112022]
        Fostier et al., 1998, Genetics 150(4): 1477--1485
        Genetic characterization of the Drosophila melanogaster suppressor of deltex gene: a regulator of Notch signaling. [FBrf0105825]
        Reichhart and Ferrandon, 1998, D. I. S. 81: 201--202
        Green balancers. [FBrf0105466]
        Speicher et al., 1994, Development 120(3): 535--544
        The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: control of cell proliferation. [FBrf0074510]
        Coyle-Thompson and Banerjee, 1993, Development 119(2): 377--395
        The strawberry notch gene functions with Notch in common developmental pathways. [FBrf0068459]
        Fleming et al., 1990, Genes Dev. 4: 2188--2201
        The gene Serrate encodes a putative EGF-like transmembrane protein essential for proper ectodermal development in Drosophila melanogaster. [FBrf0051848]
        Nicklas and Cline, 1983, Genetics 103(4): 617--631
        Vital genes that flank sex-lethal, an X-linked sex determining gene of Drosophila melanogaster. [FBrf0039466]
        Belt, 1971, D. I. S. 46: 116
        A non-lethal allele of Serrate? [FBrf0022273]
        Curry, 1939, D. I. S. 12: 45--47
        [New mutants report.] [FBrf0063388]
        Personal communication to FlyBase
        Bloomington Drosophila Stock Center, 2001.8.28, Balancer Variants.
        Balancer Variants. [FBrf0138610]
        Bloomington Drosophila Stock Center, 1999.8.10, TM3 variant.
        TM3 variant. [FBrf0109361]
        Carpenter, 1998.11.24, Info on Adelaide Carpenter's stocks.
        Info on Adelaide Carpenter's stocks. [FBrf0106081]
        Reichhart and Ferrandon, 1998.6.8, Green Balancers.
        Green Balancers. [FBrf0102825]
        FlyBase analysis
        FlyBase Curators, 2006-, Balancer summary information.
        Balancer summary information. [FBrf0189689]
        Book
        Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
        The Genome of Drosophila melanogaster. [FBrf0066905]
        Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp
        Genetic variations of Drosophila melanogaster. [FBrf0020044]