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General Information
Symbol
Dmel\skd2
Species
D. melanogaster
Name
FlyBase ID
FBal0015676
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

A small proportion of skd2 heterozygous adults show an ectopic scutellar bristle phenotype, as compared to controls.

brm2 shows little if any interaction in double heterozygous combination with skd2; less than 3% of flies have held-out wings.

Mutation does not affect the level of w expression in ph-plac+3 flies.

Associated with recessive lethality at the larval-pupal transition.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

skd2 is an enhancer of visible | dominant phenotype of tna1

NOT Enhancer of
Statement
Reference
Suppressor of
Statement
Reference

skd2 is a suppressor of lethal phenotype of Ras85DV12.sev, sevS11.Tag:MYC

NOT Suppressor of
Statement
Reference
Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

skd2 has scutellar bristle | ectopic phenotype, enhanceable by sxc[+]/sxcH537A

Enhancer of
Statement
Reference

skd2 is an enhancer of wing phenotype of tna1

NOT Enhancer of
Statement
Reference
Suppressor of
Statement
Reference

skd2 is a suppressor of eye phenotype of CycEJP

skd2/skd[+] is a suppressor | partially of adult mesothoracic segment | ectopic phenotype of E(z)Trm

skd2/skd[+] is a suppressor | partially of adult metathoracic segment phenotype of E(z)Trm

skd2/skd[+] is a suppressor | partially of adult prothoracic segment phenotype of E(z)Trm

skd2 is a suppressor of phenotype of AntpNs

skd2 is a suppressor of phenotype of Pclunspecified

skd2/skd[+] is a suppressor of phenotype of Pcunspecified

skd2 is a suppressor of phenotype of Scrunspecified

skd2 is a suppressor of phenotype of Ubxunspecified

skd2 is a suppressor of phenotype of Pc4

NOT Suppressor of
Statement
Reference

skd2 is a non-suppressor of eye phenotype of Scer\GAL4ey.PH, brmK804R.UAS.Tag:HA

Other
Statement
Reference

KrIf-1, skd2/skd[+] has eye phenotype

Additional Comments
Genetic Interactions
Statement
Reference

The ectopic scutellar bristle phenotype observed in skd2 heterozygotes is enhanced by sxcH537A heterozygosity, but is not further enhanced by sxcH537A homozygosity.

2+/-1% of KrIf-1/+ flies born to skd2/+ mothers have outgrowths with ectopic vibrissae protruding from the ventral region of the eye, compared to less than 0.1% of KrIf-1/+ flies born to isogenised wild-type mothers.

Mutant suppresses the CycEJP eye rough phenotype.

The lethality caused by sevS11.T:Hsap\MYC in combination with Ras85DV12.sev is suppressed by skd2.

Isolated as a dominant suppressor of Pc mutations. Also interacts with Pcl, Scr and Ubx mutations. May weakly suppress AntpNs.

Suppresses the extra sex comb phenotype of Pc4, Ts(YLt;2Lt)L124. Causes between 50% and 100% suppression of the Pc4/+ extra sex combs phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
References (22)