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General Information
Symbol
Dmel\sl3
Species
D. melanogaster
Name
FlyBase ID
FBal0015679
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Breakpoint of Tp(1;2)r+75c maps to the SH2-PH domain region of the sl transcription unit.

Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes show a modest reduction in wing length and a mildly rough eye. In addition, homozygotes show ectopic wing veins, most frequently adjacent to L2 but sometimes connected or adjacent to the posterior crossvein or in the posterior cell. Ommatidial array is disrupted, many ommatidia are abnormally shaped. Eyes show interommatidial bristle defects. Some are missing, some are duplicated and some appear at additional vertices. 51% of ommatidia contain extra inner photoreceptors. A small fraction of ommatidia have one or more extra (2%) or missing (10%) outer photoreceptors. The majority of supernumerary photoreceptors show an R7 identity.

Mutant eye and wing phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

sl3 is a suppressor of visible phenotype of Pp2B-14Dact.GMR

Phenotype Manifest In
Suppressor of
Statement
Reference

sl3 is a suppressor of eye phenotype of Pp2B-14Dact.GMR

sl3 is a suppressor of eye phenotype of CanBGMR.PS, Pp2B-14Dact.GMR

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Complementation data based on rough eye and wing phenotypes.

Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer

Lefevre.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
sl3
Name Synonyms
Secondary FlyBase IDs
    References (5)