Allele Dmel\sn⁴

General Information
Symbol	Dmel\sn⁴	Species	D. melanogaster
Name		FlyBase ID	FBal0015774
Feature type	allele	Associated gene	Dmel\sn

Allele class
Mutagen	spontaneous
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	spontaneous (Roiha et al., 1988, Cant et al., 1994)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Promoter is deleted, a cryptic promoter is used (sws). (Cant et al., 1994) sequence normal
Cytology
Phenotypic Data
Phenotypic Class
	female fertile (Roiha et al., 1988) fertile (Cant et al., 1994) visible (Dickinson and Thatcher, 1997)
Phenotype Manifest In
	denticle belt (Dickinson and Thatcher, 1997) macrochaeta (Roiha et al., 1988, Cant et al., 1994)
Detailed Description
	Statement Reference Mutation causes an intermediate denticle phenotype. Denticles tend to be smaller and have thinner hooks than wild-type denticles. They are also less orderly along each row and sometimes have a floppy appearance. (Dickinson and Thatcher, 1997) Bristles are bent due to disrupted actin filament bundles. (Cant et al., 1994) Weak bristle phenotype, female fertile. (Roiha et al., 1988) class 2 - female fertile with kinky macrochaetae only
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
NOT suppressed by
Statement Reference sn⁴ has phenotype, non-suppressible by su(Hw)² (Lindsley and Grell, 1968)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Kyoto	103239 C(1)DX, y¹ f¹ / cm¹ ct⁶ sn⁴ oc¹ ptg¹
Notes on Origin
Discoverer	Bridges, 30126.

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	sn⁴
Name Synonym
Secondary FlyBase IDs

References ( 7 )
Research paper	Dickinson and Thatcher, 1997, Cell Motility Cytoskel. 38(1): 9--21 Morphogenesis of denticles and hairs in Drosophila embryos: involvement of actin-associated proteins that also affect adult structures. [FBrf0098231] Cant et al., 1994, J. Cell Biol. 125(2): 369--380 Drosophila singed, a fascin homolog, is required for actin bundle formation during oogenesis and bristle extension. [FBrf0072754] Paterson and O'Hare, 1991, Genetics 129: 1073--1084 Structure and transcription of the singed locus of Drosophila melanogaster. [FBrf0054119] Roiha et al., 1988, Genetics 119: 75--83 P element insertions and rearrangements at the singed locus of Drosophila melanogaster. [FBrf0048245] Bender, 1960, Genetics 45: 867--883 Studies on the expression of various singed alleles in Drosophila melanogaster. [FBrf0013252] Hexter, 1955, Proc. Natl. Acad. Sci. U.S.A. 41: 921--925 Functional and spatial pseudoallelism at the singed locus in Drosophila. [FBrf0010365]
Book	Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp Genetic variations of Drosophila melanogaster. [FBrf0020044]

Allele Dmel\sn4

Allele Dmel\sn⁴