FB2025_01 , released February 20, 2025
Allele: Dmel\sph1
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General Information
Symbol
Dmel\sph1
Species
D. melanogaster
Name
FlyBase ID
FBal0015999
Feature type
allele
Associated gene
sph
Associated Insertion(s)
Carried in Construct
Also Known As
4P1
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Schalet and Lefevre, 1973)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos exhibit neither CNS or PNS defects.

      (Perrimon et al., 1989)

      sph1/Df(1)17-87 flies overlap wild-type at 24-25oC. At 29-30oC, sph1/Df(1)17-87 flies show sparseness of thoracic hairs, variable eye roughening, extension of the wings and incision of the wing margins.

      (Schalet and Lefevre, 1973)

      Thoracic hairs are sparse in sph1/Df(1)17-87 hemizygotes and sph1/sph22 flies, variable roughening of the eyes is seen, wings are extended and the wing margins are incised. The phenotype overlaps wild type at 24-25oC, but at 29-30oC all sph1/Df(1)17-87 flies show the mutant phenotype.

      (Schalet, 1972)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Maternal germline clonal analysis demonstrates abnormal oogenesis, collapsed eggs and some look normal.

      (Perrimon et al., 1989)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      4P1
      (Perrimon et al., 1989, Lefevre, 1981, Schalet and Lefevre, 1973, Schalet, 1972)
      l(1)4P1
      sph1
      sph4P1
      (Perrimon et al., 1989)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)