FB2025_01 , released February 20, 2025
Allele: Dmel\sph4
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General Information
Symbol
Dmel\sph4
Species
D. melanogaster
Name
FlyBase ID
FBal0016002
Feature type
allele
Associated gene
sph
Associated Insertion(s)
Carried in Construct
Also Known As
X-4, X4
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Schalet and Lefevre, 1973, Lifschytz and Falk, 1968)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      sph4/Df(1)17-87 flies overlap wild-type at 24-25oC. At 29-30oC, sph4/Df(1)17-87 flies show sparseness of thoracic hairs, variable eye roughening, extension of the wings and incision of the wing margins.

      (Schalet and Lefevre, 1973)

      Thoracic hairs are sparse in sph4/Df(1)17-87 hemizygotes and sph4/sph22 flies, variable roughening of the eyes is seen, wings are extended and the wing margins are incised. The phenotype overlaps wild type at 24-25oC, but at 29-30oC all sph4/Df(1)17-87 flies show the mutant phenotype.

      (Schalet, 1972)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Lifschytz.

      Comments
      Comments

      Complements: intro16-3-4. Complements: intro17-410. Complements: stnA16-1-49. intro16-3-4. intro17-410.

      (Munoz, 2004.1.5)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      X-4
      (Schalet and Lefevre, 1973, Schalet, 1972, Lifschytz and Falk, 1969)
      X4
      (Lifschytz and Yakobovitz, 1978, Lifschytz and Falk, 1968)
      l(1)X-4
      (Munoz, 2003.12.10)
      l(1)X4
      l(1)x-4
      (Munoz, 2004.1.5, Munoz, 2004.1.5)
      sph4
      Name Synonyms
      Secondary FlyBase IDs
        References (9)