homozygous embryos exhibit a mild invagination phenotype (approximately 35% of the placodes show an abnormal invagination).
stage 15 embryos, the genital disc precursor cells are completely missing.
mutant embryos have about 23 cells in each Malpighian tubule cell (as opposed to about 125 in wild-type).
The stomatogastric nervous system (SNS) anlage forms normally in mutant embryos. However, the stomodeal invaginations that are seen in wild-type stage 11 embryos are not seen in mutant embryos at this stage. Stage 17 mutant embryos lack SNS ganglia and nerves.
Mutant somatic clones have no effect on the lamina. Clones in the eye disc contain only isolated R8 neurons, which project to appropriate retinotopic positions in the lamina, and trigger early LPC maturation but not their neuronal differentiation.
Homozygous embryos have a reduced number of cells in the anterior Malpighian tubules compared to wild-type embryos.
Germline clones fail to rescue the female sterile phenotype of Fs(2)Ugr
Epidermal defects and fusion of the anterior and posterior commissures. In the PNS some sensory organs are missing, there is a ventral-dorsal gradient of severity. Several muscle fibres are always missing in the dorsolateral region and there are variable abnormalities in the number, shape and attachment sites of the eight ventral oblique muscle fibres.