FB2025_01 , released February 20, 2025
Allele: Dmel\Su(dx)2
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General Information
Symbol
Dmel\Su(dx)2
Species
D. melanogaster
Name
FlyBase ID
FBal0016264
Feature type
allele
Associated gene
Dmel\Su(dx)
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Lindsley and Zimm, 1992)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Su(dx)2 mutant C4da neuronal clones do not exhibit defects in dendrite pruning or neuronal cell death 18-20 hours after puparium formation.

      (Kuo et al., 2006)

      Mutants show no obvious mushroom body defect.

      (Watts et al., 2003)

      Dominantly suppresses the mutant wing eye and ocelli phenotypes of dxENU, dx1, dxP and dxS1M.

      (Busseau et al., 1994)

      Less effective than Su(dx)1 as a suppressor of dx. RK3.

      (Lindsley and Zimm, 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      Su(dx)[+]/Su(dx)2 is a non-enhancer of chemical sensitive | adult stage phenotype of Otud6C183A

      (Villa et al., 2024)

      Su(dx)[+]/Su(dx)2 is a non-enhancer of increased mortality | adult stage phenotype of Otud6C183A

      (Villa et al., 2024)
      NOT Suppressor of
      Statement
      Reference

      Su(dx)[+]/Su(dx)2 is a non-suppressor of chemical sensitive | adult stage phenotype of Otud6C183A

      (Villa et al., 2024)

      Su(dx)[+]/Su(dx)2 is a non-suppressor of increased mortality | adult stage phenotype of Otud6C183A

      (Villa et al., 2024)
      Phenotype Manifest In
      Other
      Statement
      Reference

      Su(dx)2, da2 has follicle cell phenotype

      (Smith et al., 2002)

      Su(dx)[+]/Su(dx)2, da2 has follicle cell phenotype

      (Smith et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Su(dx)sp

      (Fostier et al., 1998)
      Comments

      Su(dx)2 may simply be ed1 Su(dx)1 or it may be of independent origin. Allelism inferred from phenotype alone.

      (Lindsley and Zimm, 1992)
      Images (0)
      Mutant
      Wild-type
      Stocks (4)
      Notes on Origin
      Discoverer

      Bridges, 1st June 1931.

      (Lindsley and Zimm, 1992)

      Arose in: dx1 stock, as did Su(dx)1, along with ed1.

      (Lindsley and Zimm, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Su(dx)2
      (Villa et al., 2024, He et al., 2023, Zhu et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)