A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Allele Dmel\su(f)2

General Information
SymbolDmel\su(f)2SpeciesD. melanogaster
NameFlyBase IDFBal0016267
Feature typealleleAssociated geneDmel\su(f)
Also Known Assu(f)3DES, 3DES, l(1)3-Des
Allele class
Mutagendiethyl sulfate, ethyl methanesulfonate
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Description
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FB2013_03
FB2013_02
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Nature of the Allele
Allele class
Mutagen
diethyl sulfate
(Lifschytz and Falk, 1968, Schalet and Lefevre, 1973, Perrimon et al., 1989)
ethyl methanesulfonate
(Lifschytz and Falk, 1968)
Mutations Mapped to the Genome
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Progenitor genotype
Nature of the lesion
Statement
Reference
Nucleotide substitution at position 3606 (coordinates from FBrf0058525) that changes the AG consensus dinucleotide at the 3' splice site of intron 8 to TG.
(Simonelig et al., 1996)
Cytology
hide Phenotypic Data
hide Phenotypic Class
cell lethal | germline clone
(Perrimon et al., 1989)
lethal | recessive
(Perrimon et al., 1989, Kramers et al., 1983)
hide Phenotype Manifest In
hide Detailed Description
Statement
Reference
Lethality occurs during larval or pupal stages. Homozygous germline clones display cell lethality. Embryos derived from heterozygous mothers exhibit neither CNS or PNS defects.
(Perrimon et al., 1989)
su(f)4/su(f)2 flies are viable at 17-18oC, 24-25oC and 29-30oC, and are normal for the "pale bristles" phenotype.
(Schalet and Lefevre, 1973)
su(f)4/su(f)2 females are fully viable, show a good but not complete suppression of f1 and are normal for the su(f)4 phenotype at all temperatures.
(Schalet, 1972)
Homozygotes lethal at the larval stage; homozygous germ-line clones don't survive; no effect on development of peripheral or central nervous systems (Perrimon, Smouse, and Miklos, 1989). wa displays dilute apricot pigmentation in su(f)1/su(f)2 flies raised at 25oC but white eyes when raised at 18oC (Schalet and Lefevre, 1976). su(f)2 shown to be proximal to su(f)1 by recombination (Schalet).
 
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Linkouts
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hide Phenotypic Class
hide Phenotype Manifest In
hideSuppressor of
Statement
Reference
su(f)2 is a suppressor of phenotype of f1
(Schalet and Lefevre, 1973, Schalet, 1972)
hide Additional Comments
hide Genetic Interactions
Statement
Reference
su(f)2 lethality is unaffected by Hsap\CSTF3Scer\UAS.cBa; Scer\GAL4da.G32.
(Benoit et al., 2002)
f1 su(f)2/f1 su(f)1 flies are f+. su(f)4/su(f)2 flies show a good but not complete suppression of f1.
(Schalet and Lefevre, 1973)
f1 su(f)2/f1 su(f)1 females are f+ at 24-25oC. f1 su(f)2/f5 su(f)1 females show suppression of the f mutant phenotype similar to that seen in f1 su(f)1/f5 su(f)1 females at 24-25oC. At 20-30oC, the f1 su(f)2/f5 su(f)1 combination shows suppression of the f mutant phenotype but bristles are Minute-like.
(Schalet, 1972)
hide Xenogenetic Interactions
Statement
Reference
hide Complementation & Rescue Data
Complements
su(f)4
(Schalet, 1972)
Fails to complement
su(f)1
(Schalet, 1972)
Rescued by
su(f)2 is rescued by su(f)Scer\UAS.cAa/Scer\GAL4da.G32
(Benoit et al., 2002)
Comments
hide Stocks ( 0 )
hide Notes on Origin
Discoverer
Lifschytz.
hide Comments
Complements: stnA16-1-49. Complements: intro16-3-4. Complements: intro17-410. Complements: intro16-2-9. Complements: sph16-2-9.
(Munoz, 2004.1.5)
su(f)26, su(f)5 and su(f)2 exhibit the same pattern of complementation; complement su(f)4, su(f)13 and su(f)12. The allelic state of z has no effect on complementation behaviour.
(Simonelig et al., 1996)
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Other Crossreferences
Linkouts
hide Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym
3DES
(Kramers et al., 1983, Schalet and Lefevre, 1973, Lifschytz and Falk, 1969, Lifschytz and Falk, 1968)
l(1)3-Des
(Munoz, 2004.1.5, Munoz, 2004.1.5, Munoz, 2003.12.10)
l(1)3DES
(Miklos et al., 1986, )
lDES
(The Moscow Regional Drosophila melanogaster Stock Center, Dubna)
su(f)2
 
su(f)3DES
(Benoit et al., 2002, Simonelig et al., 1996, Schalet, 1972, Perrimon et al., 1989)
Name Synonym
Secondary FlyBase IDs
hide References ( 16 )
Research paper
Benoit et al., 2002, Proc. Natl. Acad. Sci. U.S.A. 99(16): 10593--10598
Chimeric human CstF-77/Drosophila Suppressor of forked proteins rescue suppressor of forked mutant lethality and mRNA 3' end processing in Drosophila. [FBrf0151471]
Simonelig et al., 1996, Genetics 142(4): 1225--1235
Interallelic complementation at the suppressor of forked locus of Drosophila reveals complementation between suppressor of forked proteins mutated in different regions. [FBrf0087710]
Perrimon et al., 1989, Genetics 121: 313--331
Developmental genetics of loci at the base of the X chromosome of Drosophila melanogaster. [FBrf0049891]
Miklos et al., 1986, D. I. S. 63: 96--97
The proximal-distal orientation of two lethal complementation groups A112 and LB20 in region 19F at the base of the X chromosome. [FBrf0044126]
Kramers et al., 1983, Mutat. Res. 107: 187--201
High proportion of multi-locus deletions among hycanthone-induced X-linked recessive lethals in Drosophila melanogaster. [FBrf0039985]
Schalet and Lefevre, 1973, Chromosoma 44: 183--202
The localization of 'ordinary' sex-linked genes in section 20 of the polytene X chromosome of Drosophila melanogaster. [FBrf0024685]
Voss and Falk, 1973, Mutat. Res. 20(2): 221--234
The nature of reverse mutations in Drosophila melanogaster. [FBrf0025545]
Schalet, 1972, D. I. S. 49: 36--37
[New mutants report.] [FBrf0063860]
Lifschytz and Falk, 1969, Mutat. Res. 8: 147--155
Fine structure analysis of a chromosome segment in Drosophila melanogaster. Analysis of ethyl methanesulphonate-induced lethals. [FBrf0020833]
Lifschytz and Falk, 1968, Mutat. Res. 6: 235--244
Fine structure analysis of a chromosome segment in Drosophila melanogaster. Analysis of X-ray-induced lethals. [FBrf0019966]
Schalet, 1968, D. I. S. 43: 125
Evidence for a different function associated with the locus of suppressor of forked. [FBrf0019283]
Personal communication to FlyBase
Munoz, 2004.1.5, Drosophila II.
Drosophila II. [FBrf0173252]
Munoz, 2004.1.5, Suggestions, amendments, additions.
Suggestions, amendments, additions. [FBrf0173250]
Munoz, 2003.12.10, Drosophila data.
Drosophila data. [FBrf0173246]
Stock list
The Moscow Regional Drosophila melanogaster Stock Center, Dubna, Russia, 1997, D. I. S. 80: 109--130
Stock list. [FBrf0098381]
Book
Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
The Genome of Drosophila melanogaster. [FBrf0066905]