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General Information
Symbol
Dmel\Su(H)1
Species
D. melanogaster
Name
FlyBase ID
FBal0016302
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Su(H)1/Su(H)IB115 mutant tissues exhibit a loss of ptc-positive prohemocytes and the overproduction of differentiated plasmatocytes. By contrast, an increase is not observed in the crystal cell population in Su(H)1/Su(H)IB115 mutant lymph glands.

Dorsal, ventral and dorsoventral clones that extend to the wing margin produce extensive scalloping.

Lethality during the first day of pupal development. Supernumerary cells stained in mutant imaginal discs have adopted a sensory organ precursor (SOP) fate instead of the epidermal fate they would normally express. The excess SOPs arise from the proneural clusters of potential precursor cels that appear in the imaginal discs during the development of wild type bristles. The wing pouch region of the wing imaginal disc and the retinal field of the eye-antennal imaginal disc are dramatically reduced. Identical phenotype is seen when transheterozygous with Df(2L)TE35BC-24, Su(H)IB115, Su(H)2 or Su(H)8.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhancer of
Statement
Reference

Su(H)[+]/Su(H)1 is a non-enhancer of neurophysiology defective | dominant | adult stage phenotype of DCTN1-p1501

Su(H)[+]/Su(H)1 is a non-enhancer of neuroanatomy defective | dominant | adult stage phenotype of DCTN1-p1501

Suppressor of
Statement
Reference

Su(H)[+]/Su(H)1 is a suppressor of visible | dominant phenotype of gcmPyx

Su(H)[+]/Su(H)1 is a suppressor | partially of visible | adult stage phenotype of Hsap\ATXN1LUAS.Tag:FLAG

Su(H)[+]/Su(H)1 is a suppressor of visible phenotype of Scer\GAL4Tub.PU, cswN308D.UASp

Su(H)[+]/Su(H)1 is a suppressor of lethal | pupal stage phenotype of Eps-15EP2513

Phenotype Manifest In
NOT Enhancer of
Statement
Reference

Su(H)[+]/Su(H)1 is a non-enhancer of giant fiber neuron phenotype of DCTN1-p1501

Suppressor of
Statement
Reference

Su(H)[+]/Su(H)1 is a suppressor of chaeta | supernumerary phenotype of gcmPyx

Su(H)[+]/Su(H)1 is a suppressor | partially of wing blade phenotype of Hsap\ATXN1LUAS.Tag:FLAG

Su(H)[+]/Su(H)1 is a suppressor of wing vein L5 phenotype of Hsap\ATXN1LUAS.Tag:FLAG

Su(H)[+]/Su(H)1 is a suppressor of wing vein | ectopic phenotype of Scer\GAL4Tub.PU, cswN308D.UASp

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Su(H)1/+ does not enhance the morphological or electrophysiological defects of the giant fiber axons of Gl1/+ flies.

Su(H)1 heterozygosity suppresses the lethality found in Eps-15EP2513 homozygotes. These flies do not exhibit any apparent morphological or behavioral defects.

Xenogenetic Interactions
Statement
Reference

The wing vein L5 thickening characteristic for adult females expressing Hsap\ATXN1LScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4hh.PU can be suppressed by combination with Su(H)1/+, while the loss of posterior crossvein is only partially restored.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (5)
Notes on Origin
Discoverer

Plunkett, Sep. 1924.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (22)