Open Close
General Information
Symbol
Dmel\Tlrv19
Species
D. melanogaster
Name
FlyBase ID
FBal0016861
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Tl9QRE, Toll9QRE
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
embryos laid by Tlr2/Tlrv19 mothers are dorsalised. They display differentiating amnioserosa tissue around the entire central region of the embryo. Leading edge (LE) and dorsal ectoderm are also formed in these embryos but their axial arrangement is reoriented nearly 90o. Consequently LE cells are arrayed around the dorsal ventral circumference of the embryos, rather than in an anterior to posterior orientation. However, they remain in a single row configuration between amnioserosa and dorsal ectoderm cells. many embryos display a non-uniform distribution of amnioserosa and dorsal ectoderm.
Mutant embryos do not respond to injected purified polarizing activity (spz).
Incompletely penetrant dominant dorsalization.
Dorsalized phenotype facilitates removal of perivitelline fluid.
Does not interact with RpII140wimp maternal effect.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhancer of
Statement
Reference
Tlrv19 is a non-enhancer of visible phenotype of upd1GMR.PB
NOT Suppressor of
Statement
Reference
Tlrv19 is a non-suppressor of visible phenotype of upd1GMR.PB
Phenotype Manifest In
NOT Enhancer of
Statement
Reference
Tlrv19 is a non-enhancer of eye phenotype of upd1GMR.PB
Suppressor of
Statement
Reference
Tlrv19 is a suppressor of phenotype of eaD3
Tlrv19 is a suppressor of phenotype of eaD1
NOT Suppressor of
Statement
Reference
Tlrv19 is a non-suppressor of eye phenotype of upd1GMR.PB
Additional Comments
Genetic Interactions
Statement
Reference
Perivitelline fluid from embryos laid by Tlrv13/Tlrv19 females shows polarising activity when injected into the perivitelline space of embryos derived from pip1/pip2 females.
The addition of Tlrv19/+ or baz692-44/+ has no effect on Df(2R)aEX1/+ flies.
Dominant suppressor of dominant ea ventralizing mutants. Double mutant combinations with eaD1 are strongly dorsalizing.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Comments
Comments
Injection of spz into Tl- embryos does not cause rapid degradation of cact.
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (8)
References (26)