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General Information
Symbol
Dmel\trh2
Species
D. melanogaster
Name
FlyBase ID
FBal0017037
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

T371067A

Reported nucleotide change:

T?A

Amino acid change:

I233N | trh-PA; I233N | trh-PB; I270N | trh-PC; I233N | trh-PD; I233N | trh-PE; I270N | trh-PF; I233N | trh-PG

Reported amino acid change:

I233N

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: I233N.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Single cell class IV dendrite arborisation (da) neuron clones that are homozygous for trh2 do not show defects in the establishment or maintenance of dendritic tiling.

In trh2 homozygous embryos, salivary duct cells fail to invaginate, instead remaining clustered on the surface of the embryo.

Stage 16 trh2 homozygous embryos lack all signs of a tracheal system.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Tracheal primordia development in trh2 homozygotes is rescued by trhScer\UAS.T:Zzzz\FLAG; Scer\GAL4arm.PS, but not by trhS665A.Scer\UAS.T:Zzzz\FLAG; Scer\GAL4arm.PS.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Tracheal primordia development in trh2 homozygotes is not rescued by trhS665A.Scer\UAS.T:Zzzz\FLAG; Scer\GAL4arm.PS.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (8)