Allele Dmel\tx¹

General Information
Symbol	Dmel\tx¹	Species	D. melanogaster
Name		FlyBase ID	FBal0017319
Feature type	allele	Associated gene	Dmel\tx

Allele class	hypomorphic allele - genetic evidence
Mutagen	spontaneous
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class	hypomorphic allele - genetic evidence (Howe et al., 1995, Cook and Carpenter, 2002)
Mutagen	spontaneous
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference No alteration has been detected in the coding region. (Egoz-Matia et al., 2011)
Cytology
Phenotypic Data
Phenotypic Class
	viable (Howe et al., 1995) visible (Egoz-Matia et al., 2011) visible (with tx¹⁴) (Egoz-Matia et al., 2011)
Phenotype Manifest In
	wing (Egoz-Matia et al., 2011) wing sensillum (Egoz-Matia et al., 2011) wing sensillum (with tx¹⁴) (Egoz-Matia et al., 2011)
Detailed Description
	Statement Reference Mutant wings typically have a crease lengthwise and have extra sensory bristles. tx[1]/tx[14] flies have extra sensory bristles on the wing. (Egoz-Matia et al., 2011) Homozygous mutants frequently hold out only one wing out and rarely show other wing phenotypes. tx¹/Df animals have strongly outheld wings that are thickened, slightly cupped and occasionally blistered. (Cook and Carpenter, 2002) Wings held out at about 75^o from body axis, often arched or wavy, somewhat narrow and dusky. Unable to fly because of shape and posture of wings. RK2.
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments	A series of complementation tests between tx[1] and several alleles of dei indicate that dei is allelic to tx. (Egoz-Matia et al., 2011)
Stocks ( 10 )
Bloomington	625 tx¹ 1376 hh^bar3 tx¹ 3345 Df(3R)Espl22, tx¹/TM6B, Tb¹ 604 Dp(3;3)bxd¹¹⁰, se¹ ss¹ Ubx^bx-1 tx¹/TM6B, Tb¹ 1450 ru¹ h¹ red¹ cv-c¹ Sb^sbd-2 sr¹ e^s hh^bar3 tx¹ ca¹/TM6, h^*
Kyoto	106016 tx¹ 106293 hh^bar3 tx¹ 106993 Df(3R)Espl22, tx¹/TM6B, Tb¹ 106002 Dp(3;3)bxd¹¹⁰, se¹ ss¹ Ubx^bx-1 tx¹/TM6B, Tb¹ 106318 ru¹ h¹ red¹ cv-c¹ Sb^sbd-2 sr¹ e^s hh^bar3 tx¹ ca¹/TM6, h^*
Notes on Origin
Discoverer	Collins, 30th Oct. 1924.

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	tx¹ (Egoz-Matia et al., 2011)
Name Synonym
Secondary FlyBase IDs

References ( 6 )
Research paper	Egoz-Matia et al., 2011, Dev. Biol. 351(1): 99--109 Spatial regulation of cell adhesion in the Drosophila wing is mediated by Delilah, a potent activator of βPS integrin expression. [FBrf0213026] Moehring and Mackay, 2004, Genetics 167(3): 1249--1263 The quantitative genetic basis of male mating behavior in Drosophila melanogaster. [FBrf0179348] Cook and Carpenter, 2002, D. I. S. 85: 34--37 Characterization of Tp(3;3)ME61 and genetic observations on chromosomal regions 96 and 97 of Drosophila melanogaster. [FBrf0179696] Howe et al., 1995, Genetics 140(3): 1033--1045 Cis-effects of heterochromatin on heterochromatic and euchromatic gene activity in Drosophila melanogaster. [FBrf0083203] Chiarodo et al., 1971, J. exp. Zool. 178(3): 325--329 On neurogenetic relations in Drosophila melanogaster. [FBrf0022944] Collins, 1928, Am. Nat. 62: 127--136 Taxi wings, a new useful III chromosome mutant in Drosophila melanogaster. [FBrf0001659]

Allele Dmel\tx1

Allele Dmel\tx¹