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General Information
Symbol
Dmel\upint-1
Species
D. melanogaster
Name
FlyBase ID
FBal0017634
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

80-85% of upint-1 flies hold wings ventrolaterally, 10% hold them vertically and the remainder maintain normal wing position. In many flies mesonotum indented to variable degree and at various positions; 85% in flies raised at 29oC and 45% when raised at 18oC. More extreme expression in y flies; partially dominant in y genotypes. Fate mapping indicates focus in presumptive thoracic musculature. Indirect flight muscle structure badly deranged, Z-bands disappear as muscles degenerate; also lose a 54k protein. upint-1/upint-1 adults flightless and unable to jump; upint-1/+ adults normal.

In many upint-1 flies, the dorsal thorax is indented. The position and extent of the indentation is variable with indentations observed at a higher proportion (85%) in flies raised at 29oC, than in flies raised at 18oC (45%).

100% of upint-1 flies are flightless and jumpless, regardless of temperature. 80-85% of upint-1 flies hold their wings ventrolaterally, 10% hold them vertically and the remainder have them in a normal position.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Name Synonyms
indented thorax
Secondary FlyBase IDs
    References (3)