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General Information
Symbol
Dmel\vas5
Species
D. melanogaster
Name
FlyBase ID
FBal0017849
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
vasO14
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

T15072797G

Reported nucleotide change:

A?G

Amino acid change:

I271M | vas-PA; I271M | vas-PB; I271M | vas-PC

Reported amino acid change:

I271M

Comment:

Lasko, 2000.2.7, personal communication

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: I271M.

Nucleotide substitution of ATG for ATA, (amino acid replacement of I by M) in the 425 amino stretch that is highly similar among DEAD-box proteins.

Expression Data
Reporter Expression
Additional Information
Statement
Reference

Oocytes from vas1 females express vas protein at normal levels throughout oogenesis.

 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Temperature sensitivity is restricted to the abdominal phenotype: at the restrictive temperature embryos lack abdomens.

Progeny have no abdominal defects but still lack pole cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

A weak vas allele.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
References (11)